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  1. Our knowledge of allergen structure and function continues to rise and new scientific data on the homology and cross-reactivity of allergen sources should be considered to extend the work of Lorenz et al., 2009 (...

    Authors: Matthew D Heath, Joe Collis, Toby Batten, James W Hutchings, Nicola Swan and Murray A Skinner
    Citation: World Allergy Organization Journal 2015 8:69
    Content type: Original research Published on:

  3. Asthma is a common chronic disease worldwide and Ascaris lumbricoides infection (ascariasis) is frequent in tropical regions. However, the effect of ascariasis on asthma severity has not been sufficiently explore...

    Authors: Emiro Buendía, Josefina Zakzuk, Dilia Mercado, Alvaro Alvarez and Luis Caraballo
    Citation: World Allergy Organization Journal 2015 8:58
    Content type: Original research Published on:

  4. IL-6 is a pro-inflammatory cytokine which has many well-defined effects. Its synthesis and release from mononuclear cells of drug-sensitized patients was related before to in vitro drug-allergy diagnostics but ha...

    Authors: Joseph M Baló-Banga, Katalin Schweitzer, Susan Lakatos and Sándor Sipka
    Citation: World Allergy Organization Journal 2015 8:83
    Content type: Original research Published on:

  5. To examine the evidence derived from randomized controlled clinical trials on the efficacy and safety of omalizumab compared to placebo in controlling symptoms of chronic idiopathic urticaria/chronic spontaneo...

    Authors: Diana C Carrillo, Mario Sanchez Borges, Elizabeth García, Eduardo Egea and Carlos D Serrano
    Citation: World Allergy Organization Journal 2014 7:50
    Content type: Original research Published on:

  6. In recent years, the interest of the scientific world towards vitamin D gradually increased, and several studies have been conducted to dissect its possible role in modulating the development/course of allergi...

    Authors: Auro Della Giustina, Massimo Landi, Federica Bellini, Mariangela Bosoni, Giuliana Ferrante, Marzia Onorari, Alessandro Travaglini, Giuseppe Pingitore, Giovanni Passalacqua and Salvatore Tripodi
    Citation: World Allergy Organization Journal 2014 7:75
    Content type: Review Published on:

  7. IgE-mediated food allergy is a potentially life-threatening allergic disease with an increase in prevalence in developed countries over the past 15 years. Currently, there are no approved forms of therapy and ...

    Authors: Uyenphuong H Le and A Wesley Burks
    Citation: World Allergy Organization Journal 2014 7:82
    Content type: Review Published on:

  8. Airway inflammation is considered to be the primary component contributing to the heterogeneity and severity of airway disorders. Therapeutic efficacies of diverse novel biologics targeting the inflammatory pa...

    Authors: Manali Mukherjee, Roma Sehmi and Parameswaran Nair
    Citation: World Allergy Organization Journal 2014 7:81
    Content type: Review Published on:

  9. Physical exercise has been shown to improve asthma symptoms, QoL, exercise capacity, bronchial hyperresponsiveness and lung function and is recommended as a supplementary treatment to pharmacotherapy for asthm...

    Authors: Andre Moreira, Matteo Bonini, Ruby Pawankar, Sandra D Anderson, Kai-Håkon Carlsen, Christopher Randolph, William Silvers, William Storms, John M Weiler and Sergio Bonini
    Citation: World Allergy Organization Journal 2014 7:74
    Content type: Original research Published on:

  12. Most Latin-American countries use subcutaneous immunotherapy (SCIT) extracts from the United States and Europe and sublingual immunotherapy (SLIT) from Europe, with the exception of Argentina, Brazil, Cuba and...

    Authors: Alexander Diaz Rodriguez, Alexis Labrada Rosado, Raúl Lázaro Castro Almarales and Mirta Álvarez Castelló
    Citation: World Allergy Organization Journal 2014 7:72
    Content type: Review Published on:

  13. Synthetic peptide immuno-regulatory epitopes (SPIRE) represent a new class of therapeutics for allergen immunotherapy that offer the potential to suppress the IgE-mediated allergic disease process through indu...

    Authors: Peter Socrates Creticos
    Citation: World Allergy Organization Journal 2014 7:71
    Content type: Review Published on:

  14. Chronic urticaria is defined as episodic or daily hives lasting for at least 6 weeks and impairs quality of life. Two main subtypes include chronic idiopathic (spontaneous) urticaria and inducible (physical) u...

    Authors: Paul A Greenberger
    Citation: World Allergy Organization Journal 2014 7:70
    Content type: Review Published on:

  15. Chronic rhinosinusitis (CRS) is a public health problem that has a significant socio-economic impact. Moreover, the complexity of this disease due to its heterogeneous nature based on the underlying pathophysi...

    Authors: Claus Bachert, Ruby Pawankar, Luo Zhang, Chaweewan Bunnag, Wytske J Fokkens, Daniel L Hamilos, Orathai Jirapongsananuruk, Robert Kern, Eli O Meltzer, Joaquim Mullol, Robert Naclerio, Renata Pilan, Chae-Seo Rhee, Harumi Suzaki, Richard Voegels and Michael Blaiss
    Citation: World Allergy Organization Journal 2014 7:69
    Content type: Consensus Document Published on:

  16. We recently identified T cell epitopes associated with human allergic responses. In a majority of cases, responses focused on a few immunodominant epitopes which can be predicted on the basis of MHC binding ch...

    Authors: April Frazier, Veronique Schulten, Denise Hinz, Carla Oseroff, John Sidney, Bjoern Peters and Alessandro Sette
    Citation: World Allergy Organization Journal 2014 7:68
    Content type: Review Published on:

  17. Sublingual immunotherapy (SLIT) use in the United States to date has been limited, despite common use and demonstrated efficacy elsewhere in the world. This is largely in part due to lack of FDA-approved SLIT ...

    Authors: Shelby Elenburg and Michael S Blaiss
    Citation: World Allergy Organization Journal 2014 7:67
    Content type: Review Published on:

  19. Allergen-specific immunotherapy (SIT) represents the only curative and specific way for the treatment of allergic diseases, which have reached a pandemic dimension in industrial countries affecting up to 20-30...

    Authors: Mübeccel Akdis
    Citation: World Allergy Organization Journal 2014 7:65
    Content type: Review Published on:

  20. Asthma affects mainly Venezuela’s urban and poor majority. Exacerbations bring about a high demand in health services, thus becoming a significant public health problem. In general, asthma control programs (GI...

    Authors: Arnaldo Capriles Hulett, Maria Gonzalez Yibirin, Amaris Garcia and Dollys Hurtado
    Citation: World Allergy Organization Journal 2014 7:64
    Content type: Original research Published on:

  21. German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not re...

    Authors: Eric Walter Pefura-Yone, André Pascal Kengne, Emmanuel Afane-Ze and Christopher Kuaban
    Citation: World Allergy Organization Journal 2014 7:63
    Content type: Original research Published on:

  22. Allergic rhinitis is a morbid condition that is frequently overlooked by patients and physicians. This type of atopy has not been adequately investigated in the United Arab Emirates.

    Authors: Bassam Mahboub, Suleiman Al-Hammadi, Vijayshree P Prakash, Nabil Sulaiman, Michael S Blaiss, Abdulla Al Redha and Deepa M Vats
    Citation: World Allergy Organization Journal 2014 7:62
    Content type: Original research Published on:

  23. Aspirin – exacerbated respiratory disease can prove difficult to control. Oral aspirin desensitization is effective, but has adverse effects and may not be cardio-protective at the high doses needed.

    Authors: Rachel Howe, Rita M Mirakian, Prathap Pillai, Simon Gane, Yvonne C Darby and Glenis K Scadding
    Citation: World Allergy Organization Journal 2014 7:61
    Content type: Original research Published on:

  24. IgE has long been known as a therapeutic target for allergic disease, but the difficulty has been in selecting agents that don't trigger cross linkage of IgE when bound to its high affinity receptor (FceR1) on...

    Authors: Stephen T Holgate
    Citation: World Allergy Organization Journal 2014 7:60
    Content type: Review Published on:

  25. An in vitro procedure based on a microarray containing many different allergen components has recently been introduced for use in allergy diagnosis. Recombinant and highly purified allergens belonging to diffe...

    Authors: Giovanni Melioli, Clive Spenser, Giorgio Reggiardo, Giovanni Passalacqua, Enrico Compalati, Anthi Rogkakou, Anna Maria Riccio, Elisabetta Di Leo, Eustachio Nettis and Giorgio Walter Canonica
    Citation: World Allergy Organization Journal 2014 7:59
    Content type: Original research Published on:

  26. Authors: Anahí Yáñez, Sang-Hoen Cho, Joan B Soriano, Lanny J Rosenwasser, Gustavo J Rodrigo, Klaus F Rabe, Stephen Peters, Akio Niimi, Dennis K Ledford, Rohit Katial, Flavia CL Hoyte, Leonardo M Fabbri, Juan C Celedón, Giorgio Walter Canonica, Paula Busse, Louis-Phillippe Boulet…
    Citation: World Allergy Organization Journal 2014 7:56
    Content type: Erratum Published on:

    The original article was published in World Allergy Organization Journal 2014 7:BMC1939-4551-7-8

  28. A pathological hallmark of asthma is chronic injury and repair, producing dysfunction of the epithelial barrier function. In this setting, increased oxidative stress, growth factor- and cytokine stimulation, t...

    Authors: Talha Ijaz, Konrad Pazdrak, Mridul Kalita, Rolf Konig, Sanjeev Choudhary, Bing Tian, Istvan Boldogh and Allan R Brasier
    Citation: World Allergy Organization Journal 2014 7:57
    Content type: Review Published on:

  29. In the past, asthma was considered mainly as a childhood disease. However, asthma is an important cause of morbidity and mortality in the elderly nowadays. In addition, the burden of asthma is more significant...

    Authors: Anahí Yáñez, Sang-Hoen Cho, Joan B Soriano, Lanny J Rosenwasser, Gustavo J Rodrigo, Klaus F Rabe, Stephen Peters, Akio Niimi, Dennis K Ledford, Rohit Katial, Leonardo M Fabbri, Juan C Celedón, Giorgio Walter Canonica, Paula Busse, Louis-Phillippe Boulet, Carlos E Baena-Cagnani…
    Citation: World Allergy Organization Journal 2014 7:87
    Content type: Review Published on:

  30. ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through 2014 by four allergy/immunology organizations. The...

    Authors: F Estelle R Simons, Ledit RF Ardusso, M Beatrice Bilò, Victoria Cardona, Motohiro Ebisawa, Yehia M El-Gamal, Phil Lieberman, Richard F Lockey, Antonella Muraro, Graham Roberts, Mario Sanchez-Borges, Aziz Sheikh, Lynette P Shek, Dana V Wallace and Margitta Worm
    Citation: World Allergy Organization Journal 2014 7:53
    Content type: Consensus Document Published on:

  32. Grasses and olive trees are the most common sources of allergenic pollen worldwide. Although they share some allergens, there are few studies analyzing the in vitro cross-reactivity between them. The aim was t...

    Authors: Barbara Cases, Maria Dolores Ibañez, Jose Ignacio Tudela, Silvia Sanchez-Garcia, Pablo Rodriguez del Rio, Eva A Fernandez, Carmelo Escudero and Enrique Fernandez-Caldas
    Citation: World Allergy Organization Journal 2014 7:54
    Content type: Original research Published on:

  33. Food allergy appears to be on the rise with the current mainstay of treatment centred on allergen avoidance. Mandatory allergen labelling has improved the safety of food for allergic consumers. However an addi...

    Authors: Katrina J Allen, Paul J Turner, Ruby Pawankar, Stephen Taylor, Scott Sicherer, Gideon Lack, Nelson Rosario, Motohiro Ebisawa, Gary Wong, E N Clare Mills, Kirsten Beyer, Alessandro Fiocchi and Hugh A Sampson
    Citation: World Allergy Organization Journal 2014 7:52
    Content type: Review Article Published on:

  34. The prevalence of allergy in athletes is increasing, and its risk varies across sports. The risk is dependent mainly on the ventilation rate and environmental factors; however, the prevalence of allergy in eli...

    Authors: Renata N Teixeira, Felipe AR Mendes, Milton A Martins, Timothy D Mickleborough and Celso RF Carvalho
    Citation: World Allergy Organization Journal 2014 7:2000
    Content type: Original research Published on:

  35. We have prepared this document, “Sublingual Immunotherapy: World Allergy Organization Position Paper 2013 Update”, according to the evidence-based criteria, revising and updating chapters of the originally pub...

    Authors: Giorgio Walter Canonica, Linda Cox, Ruby Pawankar, Carlos E Baena-Cagnani, Michael Blaiss, Sergio Bonini, Jean Bousquet, Moises Calderón, Enrico Compalati, Stephen R Durham, Roy Gerth van Wijk, Désirée Larenas-Linnemann, Harold Nelson, Giovanni Passalacqua, Oliver Pfaar, Nelson Rosário…
    Citation: World Allergy Organization Journal 2014 7:51
    Content type: Review Published on:

  37. The majority of drugs prescribed have not been tested in children and safety and efficacy of children’s medicines are frequently supported by low quality of evidence. Therefore, a large percentage of prescript...

    Authors: Diana Silva, Ignacio Ansotegui and Mário Morais-Almeida
    Citation: World Allergy Organization Journal 2014 7:48
    Content type: Review Published on:

  41. Authors: Ricardo Cardona Villa, Carlos Fernando Chinchilla Mejia, Ruth Helena Ramirez Giraldo, Maria Margarita Olivares Gomez, Victor Calvo and Jorge F Maspero
    Citation: World Allergy Organization Journal 2014 7(Suppl 1):40
    Content type: Poster presentation Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

  50. Smoking is considered to be the single most important preventable risk factor for respiratory symptoms. Estimating prevalence of respiratory symptoms is important since they most often precede a diagnosis of a...

    Authors: Helena Backman, Linnea Hedman, Sven-Arne Jansson, Anne Lindberg, Bo Lundbäck and Eva Rönmark
    Citation: World Allergy Organization Journal 2014 7:85
    Content type: Original research Published on:

World Allergy Organization Journal

ISSN: 1939-4551

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