Respiratory Syncytial Virus Infection: From Biology to Therapy A Perspective

Table 1 Summary of Studies Relating to RSV Infection

Area	Protein(s) Involved	Therapeutic Approach	Reference
Host	ICAM-1	Ab, antisense RNA	[87–89]
proteins	IFN-γ	Gene therapy	[48, 90, 91]
	2-5'Oligoadenylate synthetase	Gene therapy	[92]
	ERK1, 2	SMD inhibitors	[93]
	STAT-1/3	SMD inhibitors	[94]
	PKC-α	SMD inhibitors	[95]
Virus	F	Antisense RNA
proteins	NS1	siRNA	[96]
	F, G, SH, NS1, NS2, P, N	DNA vaccine	[90, 97]

ERK indicates extracellular signal-regulated kinase; PKC, protein kinase C; SMD, small molecular drug; STAT, signal transduction and activator of transcription.

ISSN: 1939-4551