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  1. Position article and guidelines

    Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–sponsored expert panel

    Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institut...

    Alkis Togias, Susan F. Cooper, Maria L. Acebal, Amal Assa’ad, James R. Baker Jr, Lisa A. Beck, Julie Block, Carol Byrd-Bredbenner, Edmond S. Chan, Lawrence F. Eichenfield, David M. Fleischer, George J. Fuchs III, Glenn T. Furuta, Matthew J. Greenhawt, Ruchi S. Gupta, Michele Habich…

    World Allergy Organization Journal 2017 10:1

    Published on: 6 January 2017

  2. Review

    Is allergic sensitization relevant in severe asthma? Which allergens may be culprits?

    Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequent...

    Carlo Lombardi, Eleonora Savi, Erminia Ridolo, Giovanni Passalacqua and Giorgio Walter Canonica

    World Allergy Organization Journal 2017 10:2

    Published on: 6 January 2017

  3. Original research

    Fatal asthma; is it still an epidemic?

    Asthma mortality has declined since the 1980s. Nevertheless the World Health Organization (WHO) identified asthma as responsible for 225.000 deaths worldwide in 2005, and 430.000 fatal cases are expected by 20...

    Andrea Vianello, Marco Caminati, Mariangiola Crivellaro, Rafi El Mazloum, Rossella Snenghi, Michele Schiappoli, Annarita Dama, Andrea Rossi, Giuliana Festi, Maria Rita Marchi, Chiara Bovo, Giorgio Walter Canonica and Gianenrico Senna

    World Allergy Organization Journal 2016 9:42

    Published on: 14 December 2016

  4. Original research

    Local allergic rhinitis: entopy or spontaneous response?

    The existence of a local allergic rhintis was proposed on the basis of the detection of nasal IgE in the absence of a systemic sensitization. Nevertheless, the significance of this phenomenon remains still unc...

    Matteo Gelardi, Antonio V. N. Guglielmi, Lucia Iannuzzi, Vitaliano Nicola Quaranta, Nicola Quaranta, Massimo Landi, Mario Correale, Annamaria Sonnante, Margherita Rossini, Maria Addolorata Mariggiò, Giorgio Walter Canonica and Giovanni Passalacqua

    World Allergy Organization Journal 2016 9:39

    Published on: 6 December 2016

  5. Review

    Asthma heterogeneity and severity

    Asthma is a common, chronic inflammatory airways disease characterized by a clinical syndrome of bronchial hyperresponsiveness, inflammation, and reversible airflow obstruction. Individuals with asthma can var...

    Tara F. Carr and Eugene Bleecker

    World Allergy Organization Journal 2016 9:41

    Published on: 29 November 2016

  6. Review

    Therapeutic interventions in severe asthma

    The present paper addresses severe asthma which is limited to 5-10% of the overall population of asthmatics. However, it accounts for 50% or more of socials costs of the disease, as it is responsible for hospi...

    Giorgio Walter Canonica, Gianenrico Senna, Patrick D. Mitchell, Paul M. O’Byrne, Giovanni Passalacqua and Gilda Varricchi

    World Allergy Organization Journal 2016 9:40

    Published on: 28 November 2016

  7. Original research

    Omalizumab for chronic urticaria in Latin America

    Chronic urticaria (CU) is defined as the spontaneous appearance of wheals, with or without angioedema, persisting for ≥6 weeks. Chronic Spontaneous Urticaria (CSU) is a type of CU which affects 0.5–1 % of the ...

    Paul Wilches, Paola Wilches, Juan Carlos Calderon, Annia Cherrez and Ivan Cherrez Ojeda

    World Allergy Organization Journal 2016 9:36

    Published on: 23 November 2016

  8. Letter to the Editor

    Effects of poor hygiene on cytokine phenotypes in children in the tropics

    We describe immune phenotypes (innate and adaptive cytokines) according to environmental exposure using latent class analysis. A total of 310 schoolchildren living in Ecuador were assayed for spontaneous cytok...

    C. A. Figueiredo, L. D. Amorim, M. Vaca, M. E. Chico, A. C. Campos, M. L. Barreto and P. J. Cooper

    World Allergy Organization Journal 2016 9:34

    Published on: 3 November 2016

  9. Position article and guidelines

    Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN)

    Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on...

    F. Braido, N. Scichilone, F. Lavorini, O. S. Usmani, L. Dubuske, L. P. Boulet, R. Mosges, C. Nunes, M. Sanchez-Borges, I. J. Ansotegui, M. Ebisawa, F. Levi-Schaffer, L. J. Rosenwasser, J. Bousquet, T. Zuberbier, G. Walter Canonica…

    World Allergy Organization Journal 2016 9:37

    Published on: 28 October 2016

  10. WAO Statement

    Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement

    One of the major concerns in the practice of allergy is related to the safety of procedures for the diagnosis and treatment of allergic disease. Management (diagnosis and treatment) of hypersensitivity disorde...

    Marek L. Kowalski, Ignacio Ansotegui, Werner Aberer, Mona Al-Ahmad, Mubeccel Akdis, Barbara K. Ballmer-Weber, Kirsten Beyer, Miguel Blanca, Simon Brown, Chaweewan Bunnag, Arnaldo Capriles Hulett, Mariana Castells, Hiok Hee Chng, Frederic De Blay, Motohiro Ebisawa, Stanley Fineman…

    World Allergy Organization Journal 2016 9:33

    Published on: 12 October 2016

    The Erratum to this article has been published in World Allergy Organization Journal 2017 10:6

  11. Meeting abstracts

    Proceedings of the 2015 WAO Symposium on Food Allergy and the Microbiome

    A1 Characterization of the immunoallergic profile towards the proteins of the wheat flour in Cuban population

    Raúl Lázaro Castro Almarales, Mary Carmen Reyes Zamora, Beatriz Tamargo, Damaris Torralba Averoff, Raysa Cruz, Yunia Oliva Diaz, Mirta Alvarez Castello, Alexander Ciria, Alexis Labrada, Maytee Mateo, Maytee Mateo, Damaris Torralba Averoff, Raysa Cruz, Yunia Oliva Diaz, Mirta Alvarez Castello, Alexander Ciria…

    World Allergy Organization Journal 2016 9(Suppl 2):30

    Published on: 11 October 2016

    This article is part of a Supplement: Volume 9 Supplement 2

  12. Consensus Document

    International Consensus (ICON): allergic reactions to vaccines

    Routine immunization, one of the most effective public health interventions, has effectively reduced death and morbidity due to a variety of infectious diseases. However, allergic reactions to vaccines occur v...

    Stephen C. Dreskin, Neal A. Halsey, John M. Kelso, Robert A. Wood, Donna S. Hummell, Kathryn M. Edwards, Jean-Christoph Caubet, Renata J. M. Engler, Michael S. Gold, Claude Ponvert, Pascal Demoly, Mario Sanchez-Borges, Antonella Muraro, James T. Li, Menachem Rottem and Lanny J. Rosenwasser

    World Allergy Organization Journal 2016 9:32

    Published on: 16 September 2016

  13. Review

    Tiotropium in asthma: what is the evidence and how does it fit in?

    Despite current therapeutic approaches asthma remains uncontrolled in a significant proportion of patients. Short-acting anticholinergic bronchodilators have a very long history of use in asthma, and recent da...

    David M. G. Halpin

    World Allergy Organization Journal 2016 9:29

    Published on: 14 September 2016

  14. Original research

    Exposure to positively- and negatively-charged plasma cluster ions impairs IgE-binding capacity of indoor cat and fungal allergens

    Environmental control to reduce the amount of allergens in a living place is thought to be important to avoid sensitization to airborne allergens. However, efficacy of environmental control on inactivation of ...

    Kazuo Nishikawa, Takashi Fujimura, Yasuhiro Ota, Takuya Abe, Kareem Gamal ElRamlawy, Miyako Nakano, Tomoaki Takado, Akira Uenishi, Hidechika Kawazoe, Yoshinori Sekoguchi, Akihiko Tanaka, Kazuhisa Ono and Seiji Kawamoto

    World Allergy Organization Journal 2016 9:27

    Published on: 6 September 2016

  15. Review

    Prevention of food and airway allergy: consensus of the Italian Society of Preventive and Social Paediatrics, the Italian Society of Paediatric Allergy and Immunology, and Italian Society of Pediatrics

    Allergic sensitization in children and allergic diseases arising therefrom are increasing for decades.

    Giuseppe di Mauro, Roberto Bernardini, Salvatore Barberi, Annalisa Capuano, Antonio Correra, Gian Luigi de’ Angelis, Iride Dello Iacono, Maurizio de Martino, Daniele Ghiglioni, Dora Di Mauro, Marcello Giovannini, Massimo Landi, Gian Luigi Marseglia, Alberto Martelli, Vito Leonardo Miniello, Diego Peroni…

    World Allergy Organization Journal 2016 9:28

    Published on: 18 August 2016

  16. Review

    The use of inhaled corticosteroids in pediatric asthma: update

    Despite the availability of several formulations of inhaled corticosteroids (ICS) and delivery devices for treatment of childhood asthma and despite the development of evidence-based guidelines, childhood asth...

    Elham Hossny, Nelson Rosario, Bee Wah Lee, Meenu Singh, Dalia El-Ghoneimy, Jian Yi SOH and Peter Le Souef

    World Allergy Organization Journal 2016 9:26

    Published on: 12 August 2016

  17. Review

    Dissemination of definitions and concepts of allergic and hypersensitivity conditions

    Allergy and hypersensitivity can affect people of any age and manifest with problems in a range of organ systems. Moreover, they can have a significant impact on the quality of life of patients and their famil...

    Luciana Kase Tanno, Moises A. Calderon, Helen E. Smith, Mario Sanchez-Borges, Aziz Sheikh and Pascal Demoly

    World Allergy Organization Journal 2016 9:24

    Published on: 9 August 2016

  18. Original research

    Assessing worldwide research activity on probiotics in pediatrics using Scopus database: 1994–2014

    A wide variety of probiotic products has been introduced into the market in the past decade. Research trends and activity on probiotics help understand how these products were evolved and their potential futur...

    Waleed M. Sweileh, Naser Y. Shraim, Samah W. Al-Jabi, Ansam F. Sawalha, Belal Rahhal, Rasha A. Khayyat and Sa’ed H. Zyoud

    World Allergy Organization Journal 2016 9:25

    Published on: 25 July 2016

  19. Review

    Eosinophilic esophagitis: published evidences for disease subtypes, indications for patient subpopulations, and how to translate patient observations to murine experimental models

    Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus and commonly classified as a Th2-type allergy. Major advances in our understanding of the EoE pathophysiology have recently be...

    Anne C. A. Mudde, Willem S. Lexmond, Richard S. Blumberg, Samuel Nurko and Edda Fiebiger

    World Allergy Organization Journal 2016 9:23

    Published on: 15 July 2016

  20. Case report

    Successful use of cyclosporine as treatment for eosinophilic cystitis: a case report

    Eosinophilic cystitis is a rare inflammatory disorder characterized by eosinophilic infiltration of all layers of the urinary bladder wall. Due to lack of consensus and potential for side effect from various t...

    Sohaib Aleem, Bharat Kumar, Mary Beth Fasano, Elizabeth Takacs and Antoine Emile Azar

    World Allergy Organization Journal 2016 9:22

    Published on: 8 July 2016

  21. Review

    Particularities of allergy in the Tropics

    Allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but aspects of their prevalenc...

    Luis Caraballo, Josefina Zakzuk, Bee Wah Lee, Nathalie Acevedo, Jian Yi Soh, Mario Sánchez-Borges, Elham Hossny, Elizabeth García, Nelson Rosario, Ignacio Ansotegui, Leonardo Puerta, Jorge Sánchez and Victoria Cardona

    World Allergy Organization Journal 2016 9:20

    Published on: 27 June 2016

  22. Review

    Eosinophilic bioactivities in severe asthma

    Asthma is clearly related to airway or blood eosinophilia, and asthmatics with significant eosinophilia are at higher risk for more severe disease. Eosinophils actively contribute to innate and adaptive immune...

    Tara F. Carr, Sergejs Berdnikovs, Hans-Uwe Simon, Bruce S. Bochner and Lanny J. Rosenwasser

    World Allergy Organization Journal 2016 9:21

    Published on: 27 June 2016

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