Table 1 Demographic and disease characteristics
Patient/ sex/ Age | Duration of asthma (yr) | Duration of EGPA(yr) | Total IgE kU/L | Eosinophil cells/mm3, (%) | Radiologic Findings | Vasculitis | Polyeuropathy | Cardiac involvement | ANCA | Azathioprine | Omalizumab Dose (mg) / treatment duration (m) | Response | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Paranasal CT | Torax CT | ||||||||||||
1.F/63 | 27 | 8 | 46.9 | 1700 (21.5) | Pansinusitis | Migratory ground glass opacities, bronchial wall thickness bronchiectasis | No | No | No | Neg | No | 150/m/48Â m | Complete |
2.F/25 | 5 | 4 | 865 | 1800 (20.2) | Pansinusitis, nasal polyposis | Ground glass opacities, bronchial wall thickness | No | No | No | Neg | No | 450/2w/15Â m Stopped | None |
3.F/52 | 24 | 21 | 11.8 | 13,480 (60) | Fronthoetmoid sinusitis, nasal polyposis | Ground glass opacities, bronchial wall thickness | Yes | No | No | Neg | No | 150/m/18Â m Stopped | None |
4.F/44 | 11 | 8 | 47.9 | 3300 (27) | Pansinusitis | Transient ground glass opacities, bronchial wall thickness, milimetric nodules | No | No | No | Neg | No | 150/m/44Â m | Complete |
5.F/47 | 12 | 4 | 134 | 1000 (15.9) | Pansinusitis | Ground glass opacities | Yes | No | No | Neg | No | 300/m/39Â m | Complete |
6.F/67 | 22 | 8 | 17.8 | 8400 (53) | Pansinusitis | Transient ground glass opacities, milmetric nodules | No | Yes | No | Pos | No | 150/m/62Â m | Complete |
7.F/62 | 19 | 4 | 114 | 1200 (20.3) | Pansinusitis | Transient ground glass opacities, bronchial wall thickness, mucous impactions | No | No | No | Neg | No | 150/m/48Â m | Complete |
8.M/36 | 7 | 7 | 108 | 2900 (26) | Pansinusitis | Peribronchial thickness, ground glass opacities dominant at left upper lobe, focal patchy infiltrations | No | No | No | Neg | No | 150/m/48Â m | Complete |
9.F/50 | 10 | 10 | 41 | 2500 (24.9) | Maxiller sinusitis, nasal poliposis | Mucous impaction, bronchial wall thickness, bronchiectasis | Yes | Yes | Yes | Neg | Yes | 150/m/42Â m | None |
10.F/40 | 11 | 8 | 142 | 1100 (14) | Pansinusitis | Subpleural ground glass opacification, pulmonary nodules | Yes | No | No | Neg | Yes | 150/m/60Â m | Partial |
11.F/52 | 19 | 3.5 | 543 | 13,600 (52.4) | Nasal poliposis | Bronchial wall thickness, sublobuler patchy infiltrations | No | No | No | Pos | No | 600/m/27Â m | None |
12.M/38 | 17 | 11 | 126 | 8900 (47.5) | Pansinusitis | Paranchimal nodules, bronchial wall thickness | Yes | No | No | Neg | No | 300/m/70Â m | Complete |
13.F/61 | 36 | 7 | 186 | 2700 (20.7) | Pansinusitis | Migratory ground glass opasities, nodules and mucus impaction | Yes | No | No | Neg | No | 300/m/64Â m | None |
14.F/45 | 21 | 8 | 321 | 2200 (21.5) | Chronic sinusitis | Bilateral bronchial wall thickness | Yes | Yes | No | Neg | Yes | 300/2w/14Â m Stopped | None |
15.F/46 | 22 | 4 | 46 | 3800 (28.8) | Frontoetmoid sinusitis, nasal polipozis | Transient ground glass opacities | No | Yes | No | Neg | No | 150/m/18Â m | Complete |
16.F/37 | 9 | 5 | 87.5 | 2700 (36.5) | Pansinusitis, nasal polyposis | Transient ground glass opacities | No | No | No | Neg | Yes | 150/m/20Â m | None |
17.F/50 | 12 | 12 | 29 | 5070 (35.9) | Pan sinusitis | Bronchial wall thickness | No | No | Yes | Neg | No | 150/m/17Â m Stopped | Complete |
18.F/28 | 5 | 2 | 71 | 1440 (15.1) | Pansinusitis | Peribronchioler ground glass opasities, micronodules | Yes | No | No | Neg | Yes | 150/m/18Â m | Complete |