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Table 3 DLQI and WPAI scores among patients with a primary diagnosis of CSU with or without angioedema

From: Differences in chronic spontaneous urticaria between Europe and Central/South America: results of the multi-center real world AWARE study

Region EU Region C/SA
PRO CSU with angioedema (n = 1721) CSU without angioedema (n = 1760) Significance Test Statistic CSU with angioedema (n = 250) CSU without angioedema (n = 182) Significance Test Statistic
DLQI: mean (SD) 9.1 (7.5) 7.6 (6.3) F = 37.28; Ρ < 0.001 7.0 (6.4) 5.9 (5.5) F = 2.23; P = 0.137
 No effect 17.8% 16.3% Chi2 = 65.413; Ρ < 0.001 24.7% 24.3% Chi2 = 4.4596; P = 0.347
 Small effect 22.5% 29.5% 27.3% 33.1%
 Moderate effect 20.7% 23.7% 21.3% 25.0%
 Very large effect 28.0% 23.2% 22.0% 15.5%
 Extremely large effect 9.5% 4.5% 4.7% 2.0%
WPAI Absenteeism: mean (SD) 9.4 (22.6) 4.4 (14.8) F = 30.72; Ρ < 0.001 14.2 (23.6) 5.0 (12.7) F = 11.67; P = 0.001
WPAI Presenteeism: mean (SD) 27.1 (27.5) 22.4 (24.2) F = 14.5; Ρ < 0.001 35.3 (33.2) 22.3 (28.9) F = 9.56; P = 0.002
WPAI Work Productivity Loss: mean (SD) 29.6 (29.4) 24.2 (25.8) F = 16.82; Ρ < 0.001 39.9 (24.9) 24.3 (30.7) F = 11.63; P = 0.001
WPAI Activity Impairment: mean (SD) 36.6 (31.9) 29.2 (28.1) F = 47.14; Ρ < 0.001 41.1 (36.2) 31.3 (31.3) F = 7.99; P = 0.005