Table 3 DLQI and WPAI scores among patients with a primary diagnosis of CSU with or without angioedema
Region EU | Region C/SA | |||||
|---|---|---|---|---|---|---|
PRO | CSU with angioedema (n = 1721) | CSU without angioedema (n = 1760) | Significance Test Statistic | CSU with angioedema (n = 250) | CSU without angioedema (n = 182) | Significance Test Statistic |
DLQI: mean (SD) | 9.1 (7.5) | 7.6 (6.3) | F = 37.28; Ρ < 0.001 | 7.0 (6.4) | 5.9 (5.5) | F = 2.23; P = 0.137 |
No effect | 17.8% | 16.3% | Chi2 = 65.413; Ρ < 0.001 | 24.7% | 24.3% | Chi2 = 4.4596; P = 0.347 |
Small effect | 22.5% | 29.5% | 27.3% | 33.1% | ||
Moderate effect | 20.7% | 23.7% | 21.3% | 25.0% | ||
Very large effect | 28.0% | 23.2% | 22.0% | 15.5% | ||
Extremely large effect | 9.5% | 4.5% | 4.7% | 2.0% | ||
WPAI Absenteeism: mean (SD) | 9.4 (22.6) | 4.4 (14.8) | F = 30.72; Ρ < 0.001 | 14.2 (23.6) | 5.0 (12.7) | F = 11.67; P = 0.001 |
WPAI Presenteeism: mean (SD) | 27.1 (27.5) | 22.4 (24.2) | F = 14.5; Ρ < 0.001 | 35.3 (33.2) | 22.3 (28.9) | F = 9.56; P = 0.002 |
WPAI Work Productivity Loss: mean (SD) | 29.6 (29.4) | 24.2 (25.8) | F = 16.82; Ρ < 0.001 | 39.9 (24.9) | 24.3 (30.7) | F = 11.63; P = 0.001 |
WPAI Activity Impairment: mean (SD) | 36.6 (31.9) | 29.2 (28.1) | F = 47.14; Ρ < 0.001 | 41.1 (36.2) | 31.3 (31.3) | F = 7.99; P = 0.005 |