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Table 2 Baseline demographic and clinical characteristics of H1- antihistamine-refractory CU patients

From: Differences in chronic spontaneous urticaria between Europe and Central/South America: results of the multi-center real world AWARE study

  Region EU Region C/SA Significance Test Statistic
Age (years) 46.0 ± 15.5 42.0 ± 13.8 F = 29.57; P < 0.001
Female: n (%) 2642 (70.8) 390 (72.3) Chi2 = 15.350; P < 0.001
BMI (kg/m2)a 26.8 ± 5.4 26.3 ± 4.2 F = 1.58; P = 0.209
 Underweight: n (%) 43 (1.3) 4 (1.7) Chi2 = 5.436; P = 0.143
 Healthy weight: n (%) 1361 (40.9) 99 (40.7)
 Overweight: n (%) 1157 (34.8) 98 (40.3)
 Obese: n (%) 764 (23.0) 42 (17.3)
Diagnosis: n (%)
 CSU only 2725 (73.1) 303 (65.3) Chi2 = 17.285; P = 0.001
 CIndU only 215 (5.8) 31 (6.7)
 Both CSU and CIndU 756 (20.3) 129 (27.8)
CSU with angioedema 1721 (46.1) 250 (50.8) Chi2 = 6.839; P = 0.03
Time since diagnosis (years) 4.8 ± 7.2 3.0 ± 4.9 F = 23.33; P < 0.001
UCT scoreb 7.8 ± 4.3 7.2 (4.1) F = 5.86; P = 0.016
UCT scores < 12: n (%)b 2277 (77.5) 391 (82.8) Chi2 = 6.867; P = 0.009
  1. CIndU chronic inducible urticaria; CSU chronic spontaneous urticaria; UCT urticaria control test
  2. aBMI data was available for 3325 patients in the EU region and 243 patients in the C/SA region: the presented proportions are based on these denominators
  3. bUCT data was available at visit 1 for 2939 patients in the EU region and 472 patients in the C/SA region: the presented proportions are based on these denominators