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Table 2 Baseline demographic and clinical characteristics of H1- antihistamine-refractory CU patients

From: Differences in chronic spontaneous urticaria between Europe and Central/South America: results of the multi-center real world AWARE study

 

Region EU

Region C/SA

Significance Test Statistic

Age (years)

46.0 ± 15.5

42.0 ± 13.8

F = 29.57; P < 0.001

Female: n (%)

2642 (70.8)

390 (72.3)

Chi2 = 15.350; P < 0.001

BMI (kg/m2)a

26.8 ± 5.4

26.3 ± 4.2

F = 1.58; P = 0.209

 Underweight: n (%)

43 (1.3)

4 (1.7)

Chi2 = 5.436; P = 0.143

 Healthy weight: n (%)

1361 (40.9)

99 (40.7)

 Overweight: n (%)

1157 (34.8)

98 (40.3)

 Obese: n (%)

764 (23.0)

42 (17.3)

Diagnosis: n (%)

 CSU only

2725 (73.1)

303 (65.3)

Chi2 = 17.285; P = 0.001

 CIndU only

215 (5.8)

31 (6.7)

 Both CSU and CIndU

756 (20.3)

129 (27.8)

CSU with angioedema

1721 (46.1)

250 (50.8)

Chi2 = 6.839; P = 0.03

Time since diagnosis (years)

4.8 ± 7.2

3.0 ± 4.9

F = 23.33; P < 0.001

UCT scoreb

7.8 ± 4.3

7.2 (4.1)

F = 5.86; P = 0.016

UCT scores < 12: n (%)b

2277 (77.5)

391 (82.8)

Chi2 = 6.867; P = 0.009

  1. CIndU chronic inducible urticaria; CSU chronic spontaneous urticaria; UCT urticaria control test
  2. aBMI data was available for 3325 patients in the EU region and 243 patients in the C/SA region: the presented proportions are based on these denominators
  3. bUCT data was available at visit 1 for 2939 patients in the EU region and 472 patients in the C/SA region: the presented proportions are based on these denominators