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Table 1 Demographic and baseline data and clinical characteristics (cross-sectional population and longitudinal population sets)

From: Improvement of patient-reported outcomes in severe allergic asthma by omalizumab treatment: the real life observational PROXIMA study

Characteristic

Cross-sectional population

N = 357

Longitudinal population

N = 123

Female

232 (65.0)

76 (61.8)

Caucasian

340 (95.2)

117 (95.1)

Age, years (mean ± SD)

50.5 ± 15.5

52.7 ± 13.6

At least one comorbidity

208 (58.3)

77 (62.6)

Asthma duration, years (mean ± SD)a

18.4 ± 14.9

19.8 ± 14.5

Age at diagnosis, years (mean ± SD)a

32.1 ± 17.4

32.7 ± 15.8

Number of asthma exacerbations during the 12 months before enrolmentb

3.6 ± 4.2

4.6 ± 4.1

ACQ total scoresc

2.4 ± 1.2

2.9 ± 1.1

Smoking history

 Non-smoker

265 (74.2)

90 (73.2)

 Former smoker

67 (18.8)

27 (22.0)

 Current smoker

25 (7.0)

6 (4.9)

FEV1 (L)d

2.0 ± 0.8

1.7 ± 0.7

IgE serum level, IU/mL, (mean ± SD)e

434.8 ± 556.4

409.3 ± 394.1

At least one concomitant pharmacological treatment for respiratory disease

122 (99.2)

Corticosteroids for systemic use

50 (40.7)

  1. Data are presented as n (%), unless otherwise specified
  2. an = 347 in cross-sectional population and n = 119 in longitudinal population
  3. bn = 330 in cross-sectional population and n = 119 in longitudinal population
  4. cn = 339 in cross-sectional population and n = 96 in longitudinal population
  5. dn = 342 in cross-sectional population and n = 121 in longitudinal population (assessed at baseline or within 3 months before enrolment)
  6. en = 252 in cross-sectional population and n = 121 in longitudinal population (assessed at baseline or within 3 months before enrolment)
  7. ACQ asthma control questionnaire, FEV1 forced expiratory volume in one second, IgE immunoglobulin E, SD standard deviation