Table 1 Evidence Profile
From: Probiotics as treatment for food allergies among pediatric patients: a meta-analysis
Certainty assessment | № of patients | Effect | Certainty | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Probiotics | Placebo | Relative (95% CI) | Absolute(95% CI) | ||
SCORAD Index (assessed with: mean difference) | ||||||||||||
2 | randomized trials | not serious | not serious | not serious | serious a | none | 209 | 205 | – | MD 1.3 lower (3.88 lower to 1.28 higher) | ⨁⨁⨁◯ MODERATE | CRITICAL |
No tolerance (assessed with: relative risk) | ||||||||||||
4 | randomized trials | serious b | not serious | not serious | serious a | none | 40/153 (26.1%) | 73/161 (45.3%) | RR 0.70 (0.39 to 1.26) | 136 fewer per 1000 (from 118 more to 277 fewer) | ⨁⨁◯◯ LOW | CRITICAL |