Table 4 Blood parameters of subjects according to their clinical benefit after treatment
Hematology | Before SLIT | After SLIT | Absolute change (after-before) | Â | |||||
|---|---|---|---|---|---|---|---|---|---|
no benefit, n = 15 | clinical benefit, n = 26 |  | no benefit, n = 15 | clinical benefit, n = 26 |  | no benefit, n = 15 | clinical benefit, n = 26 |  | |
Median (Min, Max) | Median (Min, Max) | t-test | Median (Min, Max) | Median (Min, Max) | t-test | Median (Min, Max) | Median (Min, Max) | t-test | |
red blood cell count [10A12/L] | 4.6 (4, 5.3) | 4.6 (3.9, 5.3) | 0.773 | 4.8 (3.8, 5,6) | 4.7 (3.8, 5.5) | 0.663 | 0.2 (−0.4, 0.6) | 0.1 (−0.5, 0.4) | 0.297 |
hematocrit | 0.432 (0.349, 0.487) | 0.429 (0.376, 0.482) | 0.699 | 0.437 (0.367, 0.509) | 0.433 (0.363, 0.507) | 0.886 | 0.016 (−0.036, 0.052 | 0.013 (−0.041, 0.034) | 0.586 |
hemoglobin [g/L] | 144 (111, 171) | 142 (125, 162) | 0.735 | 145 (113, 169) | 139 (114, 167) | 0.943 | 0 (−15, 14) | 0.5 (−18, 7) | 0.716 |
platelete count [10A9/L] | 268 (164, 381) | 229 (168, 373) | 0.225 | 243 (155, 378) | 231 (177, 361) | 0.460 | −5 (−107, 104) | 2.5 (−71, 36) | 0.670 |
white cell count [10A9 /L] | 5.55 (3.7, 15.2) | 5.7 (3.1, 12.3) | 0.706 | 6.1 (4.3, 12.5) | 6.1 (4.3, 10.9) | 0.795 | 0.9 (−9.4, 4.1) | 0.25 (−4, 3.8) | 0.853 |
basophils abs [10A9/L] | 0.025(0.01, 0.05) | 0.02 (0, 0.08) | 0.975 | 0.03 (0.01, 0.05) | 0.03 (0, 0.07) | 0.524 | 0 (−0.02, 0.03) | 0 (−0.02, 0.02) | 0.442 |
basophils [%] | 0.35 (0.2, 1,1) | 0.5 (0.1, 1.1) | 0.731 | 0.5 (0.2, 1) | 0.5 (0.1, 0.8) | 0.453 | 0 (−0.6, 0.7) | 0 (−0.6, 0,5) | 0.438 |
eosinophils abs [10A9/L] | 0.15 (0, 0.42) | 0.13 (0.04, 1.26) | 0.559 | 0.25 (0.07, 0.5) | 0.245 (0.12, 0.47) | 0.965 | 0.08 (−0.04, 0.27) | 0.09 (−0.8, 0.37) | 0.569 |
eosinophils [%] | 2.65 (0.1, 6.2) | 2.3 (0.5, 21.5) | 0.604 | 4.2 (1.2, 9.7) | 4.2 (1.7, 7.9) | 0.846 | 1.5 (−2, 4.2) | 1.25 (−13.6, 5.5) | 0.551 |
lymphocytes abs [10A9/L] | 1.67 (1.19, 2.56) | 1.76 (1.11, 3.03) | 0.407 | 2.43 (1.71, 3.56) | 2.17 (1.43, 4.43) | 0.463 | 0.59 (0.05, 1.92) | 0.43 (−0.38, 1.4) | 0.082 |
lymphocytes [%] | 29.9 (9.9, 41) | 30.6 (19.1, 47.9) | 0.393 | 38.7 (16.8, 57.8) | 36.9 (23.3, 50.7) | 0.323 | 7.9 (−4.1, 21.8) | 3.95 (−8.9, 18.5) | 0.043 |
monocytes abs [10A9/L] | 0.375 (0.15, 0.62) | 0.31 (0.23, 0.89) | 0.936 | 0.39 (0.3, 0.89) | 0.385 (0.21, 0.71) | 0.499 | 0.01 (−0.14, 0.35) | 0.04 (− 0.47, 0.32) | 0.603 |
monocytes [%] | 6.5 (2.4, 10.4) | 5.6 (4.1, 9) | 0.742 | 6.5 (4.7, 9.7) | 6.45 (3.8, 11.8) | 0.603 | 0.3 (−4.5, 4.2) | 0.8 (−5.2, 3.6) | 0.926 |
neutrophils abs [10A9/L] | 3.34 (1.92, 13.18) | 3.33 (1.4, 8.9) | 0.526 | 3.18 (1.61, 9.14) | 3.57 (1.63, 6.38) | 0.929 | 0.15 (−9.71, 3.15) | 0.04 (−4.87, 2.72) | 0.476 |
neutrophils [%] | 60.4 (49.7, 86.9) | 58.9 (41, 72.8) | 0.392 | 50.6 (32.2, 73) | 51.4 (35.9, 68,3) | 0.301 | −8.4 (−26.8, 1.6) | −5.25 (−24, 12.2) | 0.043 |
protein in serum [g/L] | 73 (66, 80) | 73 (66, 79) | 0.869 | 76 (67, 78) | 74 (65, 83) | 0.866 | 1 (−7, 6) | 1 (−5, 9) | 0.767 |
albumin [g/L] | 48 (43, 55) | 48 (42, 53) | 0.830 | 47 (43, 55) | 48 (39, 53) | 0.768 | 0 (−6, 8) | 0 (−5, 6) | 0.914 |
calcium [mmol/L] | 2.46 (2.31, 2.73) | 2.47 (2.3, 2.57) | 0.477 | 2.42 (2.28, 2.64) | 2.46 (2.24, 2.58) | 0.874 | −0.01 (−0.31, 0.14) | −0.01 (−0,16, 0.19) | 0.314 |
phosphor inorganic [mmol/L] | 1.08 (0.8, 1.57) | 1.17 (0.82, 1.3) | 0.677 | 1.24 (1.01, 1.51) | 1.21 (0.89, 1.54) | 0.407 | 0.19 (−0.36, 0.43) | 0.14 (−0.26, 0.41) | 0.431 |
urea nitrogen [mmol/L] | 4.4 (2.6, 7.8) | 4.6 (2.4, 7.3) | 0.783 | 4.7 (3.3, 6.3) | 4.9 (3, 7.1) | 0.767 | 0.3 (−1.6, 2.8) | 0.2 (−2.4, 3) | 0.835 |
bilirubin [umol/L] | 9.5 (5, 16) | 10 (4, 35) | 0.205 | 8 (4, 13) | 8 (4, 25) | 0.064 | −2 (−9, 5) | −1 (− 12, 8) | 0.898 |
alkaline phosphatase [U/L] | 57 (43, 74) | 64 (31, 92) | 0.253 | 59 (47, 94) | 70 (29, 104) | 0.369 | 2 (−12, 38) | 4 (−8, 33) | 0.918 |
ASAT (SGOT) [U/L] | 20.5 (15,40) | 19 (16, 29) | 0.394 | 20 (12, 36) | 18 (13, 30) | 0.055 | 0 (−6, 15) | −1 (−9, 8) | 0.211 |
ALAT (SGPT) [U/L] | 12 (6, 48) | 13 (7, 34) | 0.584 | 15 (7, 46) | 13 (7, 50) | 0.134 | 1 (−11, 40) | 0 (−14, 20) | 0.277 |
lactic dehydrogenase [U/L] | 157 (113, 200) | 148 (111, 178) | 0.141 | 159 (115, 188) | 146 (116, 184) | 0.640 | 0 (−34, 22) | 5 (−16, 26) | 0.137 |
creatinine [umol/L] | 71.6 (59.8, 113.4) | 75.9 (56.8, 101.4) | 0.588 | 70.7 (60.7, 113.3) | 72.5 (57.5, 103.1) | 0.845 | −2.2 (−7.7, 12.1) | 1.1 (−34, 11.3) | 0.662 |
glucose [mmol/L] | 4.8 (3.7, 6) | 5 (3.8, 5.8) | 0.261 | 4.9 (3.7, 12.1) | 4.9 (3.4, 7.9) | 0.281 | 0.7 (−0.7, 6.1) | −0.1 (−1.3, 2.9) | 0.062 |
potassium [mmol/L] | 4.55 (3.9, 5.2) | 4.4 (3.8, 5.1) | 0.014 | 4.4 (3.9, 5.4) | 4.2 (3.9, 4.9) | 0.045 | −0.2 (− 0.9, 1) | −0.1 (− 0.5, 0.5) | 0.512 |
sodium [mmol/L] | 139 (137, 144) | 140 (137, 141) | 0.975 | 140 (137, 141) | 139 (137, 145) | 0.699 | −1 (−4, 3) | 0 (− 1, 4) | 0.782 |
chloride [mmol/L] | 103 (100, 106) | 104 (101, 106) | 0.832 | 104 (98, 106) | 104 (100, 109) | 0.768 | 2 (−5, 4) | 1 (− 4, 5) | 0.958 |
carbon dioxide, CO2 [mmol/L] | 21 (17, 24) | 22 (17, 25) | 0.388 | 23 (18, 26) | 22 (18, 25) | 0.183 | 1 (−3 7) | 0 (−6, 6) | 0.183 |