Table 3 Demographics, specific IgE and symptom scores in subjects according to clinical benefit
Parameter Median (Min,Max) | non-responders, n = 15 | responders, n = 26 | t test |
|---|---|---|---|
 Age, y | 24.4 (20.5, 42.8) | 26.4 (20.0, 53.4) | 0.859 |
 women/men | 9/6 | 14/12 |  |
Before SLIT | |||
 Der f - IgE, kUA/l | 15 (2.8, 67.9) | 13 (0.9, > 100) | 0.904 |
 TNSS | 6.5 (3.8, 10.3) | 7.7 (5.4, 11.8) | 0.023 |
After SLIT | |||
 Der f - IgE, kUA/l | 24.9 (2.2, > 100) | 25.8 (1.3, > 100) | 0.303 |
 TNSS | 8.1 (4.7, 12.0) | 3.8 (0.5, 7.3) | 3 × 10^-9 |
Absolute change (after-before) | |||
 Der f - IgE, kUA/l | 1.7 (−40.3, 84.3) | 6.2 (−14.5, 81.5) | 0.310 |
 TNSS | 1.5 (−1.3,3.2) | −4.2 (−8.5, − 1.8) | 2 × 10^-14 |
% improvement | −21 (−56, 18) | 58 (20, 92) | 4 × 10^-15 |