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Table 2 Blood parameters in placebo and active SLIT groups and their absolute change

From: Clinical efficacy of sublingual immunotherapy is associated with restoration of steady-state serum lipocalin 2 after SLIT: a pilot study

Hematology Before SLIT T-test After SLIT t-test Absolute change (after-before)  
Placebo, n = 10 Active, n = 31 Placebo, n = 10 Active, n = 31 Placebo, n = 10 Active, n = 31  
Median (Min, Max) Median (Min, Max) Median (Min, Max) Median (Min, Max) Median (Min, Max) Median (Min, Max) t-test
red blood cell count [10″ 12/L] 4.9 (4, 5.3) 4.5 (3.9, 5.3) 0.190 5.2 (4.3, 5.6) 4.55 (3.8, 5.5) 0.017 0.3 (−0.4, 0.6) 0.100 (− 0.5, 0.4) 0.062
hematocrit 0.441 (0.363, 0.487) 0.424 (0.349, 0.484) 0.379 0.47 (0.367,0.509) 0.429 (0.363,0.507) 0.131 3.026 (−0.036,0.052)0.013 (− 0.041,0.037) 0.367
hemoglobin [g/L] 148 (113, 161) 141 (111, 171 0.458 149 (113, 169) 139 (114, 167) 0.136 2 (−15, 14) -1 (−18,8) 0.299
platelete count [10A9/L] 259 (164, 329) 229 (168, 381) 0.582 242 (159, 378) 235 (155, 361) 0.532 5 (−107, 104) 2 (−96, 62) 0.635
white cell count [10A9 /L] 5.75 (3.7, 15.2) 5.7 (3.1, 12.3) 0.465 6.4 (5.3, 9.3) 6 (4.3, 12.5) 0.763 1.1 (−9.4, 2.7) 0.3 (−4, 4.1) 0.579
basophils abs [10A9/L] 0.02 (0.01,0.05) 0.03 (0, 0.08) 0.413 0.03 (0,0.05) 0.03 (0.01,0.07) 0.530 0 (−0.02, 0.03) 0.00 (− 0.02, 0.03) 0.768
basophils [%] 0.3 (0.2, 1.1) 0.5 (0.1, 1.1) 0.359 0.5 (0.1, 0.6) 0.5 (0.2, 1) 0.467 0.1 (−0.6, 0.3) 0.0 (−0.6, 0.7) 0.920
eosinophils abs [10A9/L] 0.09 (0, 0.3) 0.14 (0.04, 1.26) 0.215 0.22 (0.07, 0.47) 0.25 (0.12, 0.5) 0.578 0.11 (−0.03,0.37) 0.09 (−0.8, 0.33) 0.357
eosinophils [%] 2 (0.1, 4) 2.5 (0.5,21.5) 0.245 3.5 (1.2, 7) 4.25 (1.7, 9.7) 0.304 1.5 (−2,5.5) 1.25 (−13.6,4.2) 0.615
lymphocytes abs [10A9/L] 1.66 (1.19,2.56) 1.73 (1.11,3.03) 0.727 2.77 (1.83, 3.56) 2.15 (1.43, 4.43) 0.114 0.97 (0.04, 1.92) 0.43 (−0.38, 1.4) 0.019
lymphocytes [%] 29.8 (9.9, 41) 30.6 (19.1,47.9) 0.573 38.7 (29.6, 57.8) 37.2 (16.8, 50.7) 0.204 10.1 (−0.4,21.8) 3.85 (−8.9, 18.6) 0.052
monocytes abs [10 A9/L] 0.345 (0.22, 0.62) 0.32 (0.15, 0.89) 0.911 0.39 (0.37, 0.6) 0.38 (0.21,0.89) 0.652 0.04 (−0.07,0.32) 0.03 (−0.47, 0.35) 0.632
monocytes [%] 5.7 (2.9, 10) 5.7 (2.4, 10.4) 0.852 6.4 (4.7, 9.7) 6.55 (3.8, 11.8) 0.744 0.3 (−2.2, 3.6) 0.6 (−5.2, 4.2) 0.745
neutrophils abs [10A9/L] 3.55 (1.92, 13.18) 3.33 (1.4, 8.93) 0.310 3.32 (1.7,5.41) 3.31 (1.61,9.14) 0.752 0.22 (−9.71,0.8) 0.04 (−4.87, 3.15) 0.199
neutrophils [%] 62.1 (49.7,86.9) 58.9 (41,72.8) 0.343 53.3 (32.2, 60.1) 50.6 (34.4, 73) 0.330 −8.5 (−26.8,-5.8) −5.15 (− 24.6, 12.2) 0.050
protein in serum [g/L] 72 (69, 80) 74 (66, 79) 0.846 76 (68, 78) 74 (65, 83) 0.686 1 (−7,6) 1 (− 7, 9) 0.747
albumin [g/L] 48.5 (44, 55) 48 (42, 53) 0.567 52 (43, 55) 48 (39, 53) 0.182 0 (−6, 8) 0 (−5, 6) 0.515
calcium [mmol/L] 2.49 (2.31,2.57) 2.45 (2.3, 2.73) 0.862 2.42 (2.34, 2.64) 2.45 (2.24, 2.58) 0.786 −0.03 (−0.16, 0.14) −0.01 (−0.31,0.19) 0.812
phosphor inorganic [mmol/L] 1.08 (0.83, 1.57) 1.14 (0.8, 1.3) 0.772 1.24 (1.01, 1.47) 1.21 (0.89, 1.54) 0.502 0.19 (−0.36,0.41) 0.15 (−0.26, 0.43) 0.962
urea nitrogen [mmol/L] 4.5 (3.5, 7.5) 4.4 (2.4, 7.8) 0.631 5.5 (4.4, 6.3) 4.7 (3,7.1) 0.112 0.3 (−1.5, 2.8) 0.2 (−2.4, 3) 0.678
bilirubin [umol/L] 10 (5,20) 10 (4, 35) 0.582 8 (5, 10) 8 (4, 25) 0.123 0 (−12, 2) −1 (− 10,8) 0.397
alkaline phosphatase [U/L] 55 (43, 69) 62 (31,92) 0.264 60 (47, 86) 65 (29, 104) 0.430 4 (−12, 34) 3 (−8, 38) 0.843
AS AT (SGOT) [U/L] 20 (15, 30) 20 (16, 40) 0.710 20 (12, 36) 19 (13, 35) 0.518 1 (−5, 15) −1 (−9, 10) 0.240
ALAT (SGPT) [U/L] 12 (7,39) 13 (6, 48) 0.836 14 (7,39) 13 (7,50) 0.635 2 (−4, 24) −1 (− 14,40) 0.522
lactic dehydrogenase [U/L] 157 (113,200) 148 (111, 178) 0.147 160 (115, 188) 146 (116, 184) 0.472 2 (−34, 22) 5 (−16, 26) 0.224
creatinine [umol/L] 72.6 (65.9, 96.5) 74.3 (56.8, 113.4) 0.599 72 (63.8, 103.1) 71.7 (57.5, 113.3) 0.987 −2.2 (−7.7, 12.1) −0.1 (− 34, 11.3) 0.500
glucose [mmol/L] 4.9 (3.8, 5.8) 5 (3.7, 6) 0.728 4.8 (3.4, 5.7) 4.9 (3.9, 12.1) 0.317 −0.2 (−1.2, 1) 0.2 (− 1.3, 6.1) 0.480
potassium [mmol/L] 4.45 (4.1, 5.2) 4.4 (3.8, 5.1) 0.158 4.3 (3.9, 5.4) 4.3 (3.9, 5.1) 0.491 −0.2 (−0.9, 1) − 0.1 (− 0.5, 0.5) 0.392
sodium [mmol/L] 140 (138, 142) 140 (137, 144) 0.111 140 (137, 145) 139 (137, 142) 0.069 −1 (−3, 4) 0 (−4, 3) 0.814
chloride [mmol/L] 104 (101, 106) 103 (100, 106) 0.275 104 (98, 109) 104 (98, 108) 0.733 0 (−4, 5) 1 (−5, 4) 0.952
carbon dioxide, C02 [mmol/L] 21 (17, 24) 21 (17, 25) 0.496 23 (18, 26) 22 (18, 25) 0.077 2 (−3,7) 0 (−6, 6) 0.158