Table 1 Sensitivity and specificity (95% confidence intervals) of ISAC allergens for prediction of skin prick test (SPT) results and of SPT results for prediction of ISAC112 results are shown
ISAC with respect to SPT | SPT with respect to ISAC | ||||
|---|---|---|---|---|---|
SPT | ISAC112 allergen | Sensitivity (95% CI) | Specificity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) |
Alder | Cor a 1.0401 | 100 (81.5–100) | 77.3 (67.7–85.2) | 45.0 (29.3–61.5) | 100 (95.2–100) |
Birch | Bet v 1 | 97.8 (88.2–99.9) | 77.4 (67.6–85.4) | 67.7 (54.9–78.8) | 98.6 (92.6–100) |
Hazel | Bet v 1 | 92.9 (66.1–99.8) | 65.3 (55.2–74.5) | 27.1 (15.3–41.8) | 98.5 (92.0–100) |
Ash Tree | Ole e 1 | 86.2 (68.3–96.1) | 81.6 (72.5–88.7) | 58.1 (42.1–73.0) | 95.2 (88.3–98.7) |
Grass | Phl p 1 | 92.3 (83.0–97.5) | 75.9 (66.7–83.6) | 69.8 (58.9–79.2) | 94.3 (87.1–98.1) |
Ambrosia | Art v 1 | 61.5 (40.6–79.8) | 90.0 (82.4–95.1) | 61.5 (40.6–79.8) | 90.0 (82.4–95.1) |
Buckhorn | Phl p 5 | 87.5 (61.7–98.4) | 78.4 (68.8–86.1) | 40.0 (23.9–57.9) | 97.4 (91.0–99.7) |
HDM 1 | Der f 2 & Phl p 5 | 85.7 (69.7–95.2) | 73.5 (63.9–81.8) | 52.6 (39.0–66.0) | 93.8 (86.0–97.9) |
HDM 2 | Der f 2 | 75.8 (57.7–88.9) | 91.4 (84.4–96.0) | 73.5 (55.6–87.1) | 92.3 (85.4–96.6) |
Cat | Fel d 1 | 84.4 (67.2–94.7) | 75.0 (65.7–82.8) | 50.0 (36.1–63.9) | 94.2 (87.0–98.1) |
Dog | Can f 1 & Ole e 1 | 85.7 (57.2–98.2) | 70.0 (60.5–78.4) | 26.7 (14.6–41.9) | 97.5 (91.2–97) |
Alternaria | Alt a 1 & Can f 1 | 100 (69.2–100) | 82.6 (74.1–89.2) | 34.5 (17.9–54.3) | 100 (96.0–100) |
Mugwort | Sal k 1 | 20.0 (0.5–71.6) | 100 (96.7–100) | 61.5 (40.6–79.8) | 90.0 (82.4–95.1) |