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Table 1 Sensitivity and specificity (95% confidence intervals) of ISAC allergens for prediction of skin prick test (SPT) results and of SPT results for prediction of ISAC112 results are shown

From: Allergy diagnosis from symptoms to molecules, or from molecules to symptoms: a comparative clinical study

   ISAC with respect to SPT SPT with respect to ISAC
SPT ISAC112 allergen Sensitivity
(95% CI)
Specificity
(95% CI)
Specificity
(95% CI)
Sensitivity
(95% CI)
Alder Cor a 1.0401 100 (81.5–100) 77.3 (67.7–85.2) 45.0 (29.3–61.5) 100 (95.2–100)
Birch Bet v 1 97.8 (88.2–99.9) 77.4 (67.6–85.4) 67.7 (54.9–78.8) 98.6 (92.6–100)
Hazel Bet v 1 92.9 (66.1–99.8) 65.3 (55.2–74.5) 27.1 (15.3–41.8) 98.5 (92.0–100)
Ash Tree Ole e 1 86.2 (68.3–96.1) 81.6 (72.5–88.7) 58.1 (42.1–73.0) 95.2 (88.3–98.7)
Grass Phl p 1 92.3 (83.0–97.5) 75.9 (66.7–83.6) 69.8 (58.9–79.2) 94.3 (87.1–98.1)
Ambrosia Art v 1 61.5 (40.6–79.8) 90.0 (82.4–95.1) 61.5 (40.6–79.8) 90.0 (82.4–95.1)
Buckhorn Phl p 5 87.5 (61.7–98.4) 78.4 (68.8–86.1) 40.0 (23.9–57.9) 97.4 (91.0–99.7)
HDM 1 Der f 2 &
Phl p 5
85.7 (69.7–95.2) 73.5 (63.9–81.8) 52.6 (39.0–66.0) 93.8 (86.0–97.9)
HDM 2 Der f 2 75.8 (57.7–88.9) 91.4 (84.4–96.0) 73.5 (55.6–87.1) 92.3 (85.4–96.6)
Cat Fel d 1 84.4 (67.2–94.7) 75.0 (65.7–82.8) 50.0 (36.1–63.9) 94.2 (87.0–98.1)
Dog Can f 1 &
Ole e 1
85.7 (57.2–98.2) 70.0 (60.5–78.4) 26.7 (14.6–41.9) 97.5 (91.2–97)
Alternaria Alt a 1 &
Can f 1
100 (69.2–100) 82.6 (74.1–89.2) 34.5 (17.9–54.3) 100 (96.0–100)
Mugwort Sal k 1 20.0 (0.5–71.6) 100 (96.7–100) 61.5 (40.6–79.8) 90.0 (82.4–95.1)