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Table 6 Strength of association of family factor with AR manifestation

From: Epidemiology of allergic rhinitis and associated risk factors in Asia

Study

Study population, N

OR/PRa

Values (95% CI)

p-value

References

Age of gestation

 Lee et al., 2017 [42]

1497

OR

0.51

< 0.05

Preterm in ref. to term

 Li et al., 2015 [22]

20,803

OR

1.07 (0.88 - 1.30)

< 0.001

Preterm in ref. to term

  

1.42 (1.20 - 1.69)

< 0.001

Post-term in ref. to term

Mother depression

 Li et al., 2015 [22]

20,803

OR

1.16 (1.05 - 1.29)

< 0.05

Mother with pre- or postnatal depression in ref. to without

Mode of delivery

 Li et al., 2015 [22]

20,803

OR

1.36 (1.23 - 1.49)

< 0.001

Cesarean in ref. to vaginal delivery

Breastfeeding

 Huang et al., 2017 [34]

13,335

OR

0.97 (0.94 - 0.99)

< 0.05

With exclusive for > 6 months breastfeeding in ref. to never breastfeeding

: OR adjusted for family atopy, gender, age, district of the current residence, home ownership, early pet-keeping, parental smoking, and home dampness

 Li et al., 2015 [22]

20,803

OR

0.67 (0.61 – 0.73)

< 0.001

With exclusive breastfeeding in the first 4 months in ref. to without

Maternal education

Li et al., 2015 [22]

20,803

OR

1.55 (1.36 - 1.77)

< 0.001

High school in ref. to middle school or below

  

2.11 (1.86 - 2.39)

< 0.001

College or above in ref. to middle school or below

Paternal education

 Li et al., 2015 [22]

20,803

OR

1.52 (1.32 - 1.74)

< 0.001

High school in ref. to middle school or below

  

2.02 (1.77 - 2.30)

< 0.001

College or above in ref. to middle school or below

Gruel introduction

 Huang et al., 2017 [34]

13,335

OR

0.95 (0.90 - 1.00)

< 0.05

For > 6 months-old in ref. to < 3 months-old

: OR adjusted for family atopy, gender, age, district of the current residence, home ownership, early pet-keeping, parental smoking, and home dampness

Family history of atopy

 Bunnag et al., 2000 [37]

3124

OR

1.96 (1.56 - 2.46)

< 0.05

With family history of atopy in ref. to without: adjusted OR

Family history of allergic diseases

 Alsowaidi et al., 2010 [3]

7550

OR

6.08 (4.93 - 7.50)

< 0.0005

With family history of AR in ref. to without

: OR adjusted for nationality, gender, age, and education

 Li et al., 2014 [7]

9899

OR

3.51 (2.65 - 4.64)

< 0.001

With family history of AR in ref. to without

 Graif et al., 2004 [38]

10,057

OR

1.30 (1.02 - 1.66)

–

With family history of asthma in ref. to without: OR adjusted for current asthma, gender, gender, gender, and smoking

 Norbäck et al., 2016 (2) [35]

462

OR

3.49 (1.97 - 6.20)

< 0.001

With family history of allergic reactions in ref. to without: OR adjusted for gender, smoking, atopy, and race

 Ziyab, 2017 [8]

1154

PR

1.82 (1.39 - 2.39)

< 0.001

With maternal allergy in ref. to without: PR adjusted for gender, cat exposure, and age

  

1.87 (1.25 - 2.77)

< 0.005

With paternal allergy in ref. to without: PR adjusted for gender, cat exposure, and age

  1. aOR odds ratio, PR prevalence ratio