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Table 6 Differences in the approach to the management of CSU in respondents who do and do not follow the guidelines

From: Management of chronic spontaneous urticaria: a worldwide perspective

Test

Compared groups

n

% (n) of physicians, who follow the guidelines

% (n) of physicians, who don’t follow the guidelines

X2

p

CBC

Order

854

79.2 (802)

60.5 (52)

16.011

< 0.001

No

245

20.8 (211)

39.5 (34)

ESR

Order

602

55.9 (566)

41.9 (36)

6.284

0.012

No

497

44.1 (447)

58.1 (50)

CRP

Order

527

49.0 (496)

36.0 (31)

5.299

0.021

No

572

51.0 (517)

64.0 (55)

Anti-TG/TPO

Order

559

51.9 (526)

38.4 (33)

5.826

0.016

No

540

48.1 (487)

61.6 (53)

TSH

Order

543

50.8 (515)

32.6 (28)

10.598

0.001

No

556

49.2 (498)

67.4 (58)

Total IgE

Order

481

56.1 (445)

58.1 (36)

0.138

0.710

No

618

43.9 (568)

41.9 (50)

ECP

Order

51

4.7 (48)

3.5 (3)

0.280

0.597

No

1048

95.3 (965)

96.5 (83)

D-dimer

Order

54

5.2 (53)

1.2 (1)

2.809

0.094

No

1045

94.8 (960)

98.8 (85)

Skin prick tests

Order

308

71.4 (290)

79.1 (18)

2.329

0.127

No

791

28.6 (723)

20.9 (68)

Allergen-specific IgE

Order

286

26.5 (268)

20.9 (18)

1.257

0.262

No

813

73.5 (745)

79.1 (68)

ANA

Order

407

37.7 (382)

29.1 (25)

2.538

0.111

No

692

62.3 (631)

70.9 (61)

Tryptase

Order

162

84.9 (153)

89.5 (9)

1.357

0.244

No

937

15.1 (860)

10.5 (77)

ASST

Order

186

17.7 (179)

8.1 (7)

5.121

0.024

No

913

82.3 (834)

91.9 (79)

Search for chronic infections

Perform

364

66.2 (342)

74.4 (22)

2.394

0.122

No

735

33.8 (671)

25.6 (64)

Do not order any tests

182

15.4 (156)

30.2 (26)

12.621

< 0.001

Order at least 1 test

917

84.6 (857)

69.8 (60)

  1. CBC complete blood count, ESR erythrocyte sedimentation rate, CRP C-reactive protein, TG/TPO thyroglobulin/thyroperoxidase, TSH thyroid-stimulating hormone, ECP eosinophil cationic protein, ANA antinuclear antibodies, ASST autologous serum skin test
  2. Values marked in bold indicate a statistically significant difference (p < 0.05)