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Table 6 Differences in the approach to the management of CSU in respondents who do and do not follow the guidelines

From: Management of chronic spontaneous urticaria: a worldwide perspective

Test Compared groups n % (n) of physicians, who follow the guidelines % (n) of physicians, who don’t follow the guidelines X2 p
CBC Order 854 79.2 (802) 60.5 (52) 16.011 < 0.001
No 245 20.8 (211) 39.5 (34)
ESR Order 602 55.9 (566) 41.9 (36) 6.284 0.012
No 497 44.1 (447) 58.1 (50)
CRP Order 527 49.0 (496) 36.0 (31) 5.299 0.021
No 572 51.0 (517) 64.0 (55)
Anti-TG/TPO Order 559 51.9 (526) 38.4 (33) 5.826 0.016
No 540 48.1 (487) 61.6 (53)
TSH Order 543 50.8 (515) 32.6 (28) 10.598 0.001
No 556 49.2 (498) 67.4 (58)
Total IgE Order 481 56.1 (445) 58.1 (36) 0.138 0.710
No 618 43.9 (568) 41.9 (50)
ECP Order 51 4.7 (48) 3.5 (3) 0.280 0.597
No 1048 95.3 (965) 96.5 (83)
D-dimer Order 54 5.2 (53) 1.2 (1) 2.809 0.094
No 1045 94.8 (960) 98.8 (85)
Skin prick tests Order 308 71.4 (290) 79.1 (18) 2.329 0.127
No 791 28.6 (723) 20.9 (68)
Allergen-specific IgE Order 286 26.5 (268) 20.9 (18) 1.257 0.262
No 813 73.5 (745) 79.1 (68)
ANA Order 407 37.7 (382) 29.1 (25) 2.538 0.111
No 692 62.3 (631) 70.9 (61)
Tryptase Order 162 84.9 (153) 89.5 (9) 1.357 0.244
No 937 15.1 (860) 10.5 (77)
ASST Order 186 17.7 (179) 8.1 (7) 5.121 0.024
No 913 82.3 (834) 91.9 (79)
Search for chronic infections Perform 364 66.2 (342) 74.4 (22) 2.394 0.122
No 735 33.8 (671) 25.6 (64)
Do not order any tests 182 15.4 (156) 30.2 (26) 12.621 < 0.001
Order at least 1 test 917 84.6 (857) 69.8 (60)
  1. CBC complete blood count, ESR erythrocyte sedimentation rate, CRP C-reactive protein, TG/TPO thyroglobulin/thyroperoxidase, TSH thyroid-stimulating hormone, ECP eosinophil cationic protein, ANA antinuclear antibodies, ASST autologous serum skin test
  2. Values marked in bold indicate a statistically significant difference (p < 0.05)