Skip to main content

Table 4 Classification of angioedema

From: The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update

Bradykinin-induced AE

Mast Cell Mediator induced AE

Unknown mediator

C1-INH deficiency/defect

C1-INH normal

IgE mediated

non-IgE mediated

 

Inherited

Acquired

Inherited

Acquired

   

HAE-1

HAE-2

AAE-C1-INH

HAE nC1-INH (HAE-FXII, HAE-ANGPTI, HAE-PLG, HAE-UNK)

ACEI-AE

Angioedema with AnaphylaxisUrticaria

Angioedema with urticaria

Idiopathic AE

  1. HAE-1 hereditary angioedema due to C1-Inhibitor deficiency, HAE-2 hereditary angioedema due to C1-Inhibitor dysfunction, AAE-C1-INH acquired angioedema due to C1-Inhibitor deficiency, HAE nC1-INH hereditary angioedema with normal C1-Inhibitor levels, either due to a mutation in FXII, ANGPTI, PLG or unknown (HAE-FXII, HAE-ANGPTI, HAE-PLG, HAE-UNK), ACEI-AE angiotensin converting enzyme inhibitor-induced angioedema
Back to article page

World Allergy Organization Journal

ISSN: 1939-4551

Contact us