Table 2 Excerpt of studies on asthma epidemiology (ref 5, 6, 8), asthma symptoms (female sex hormones: ref. 33, 38, 40, 45; gender specific: ref. 52, 53) and asthma therapy (ref 61, 62)
From: Gender aspects and influence of hormones on bronchial asthma – Secondary publication and update
Trial design | Results | Reference |
|---|---|---|
5128 subjects Cohort study | Asthma incidence higher in women than men; female predominance stronger in non-sensitized adults | [5] |
1226 asthmatic patients Cross-sectional survey | Younger women have lower quality of life and less asthma control than men | [6] |
8607 subjects Cohort study | Obesity and asthma are correlated in 6–7 year old children but not in 13–14 year old teenagers | [8] |
571 women Population-based cohort study | Variation of bronchial hyperreactivity during menstruation due to hormonal influences | [33] |
2322 women Population-based cohort study | The odds of new onset asthma are increased in early postmenopausal women | [38] |
2206 women Population-based cohort study | Hormone replacement therapy and overweight increase the risk of asthma | [40] |
1438 women Population-based cohort study | Lung function decline is more rapid among post-menopausal women; respiratory health often deteriorates during reproductive aging | [45] |
1248 children Population-based study; Secondary analysis | Girls with asthma have higher physical tobacco dependence scores compared to girls without asthma | [52] |
3700 non-asthmatics 746 asthmatics Observational cohort study | Asthma is associated with increased risk of new onset chronic migraine; higher risk with higher number of respiratory symptoms | [53] |
122 asthmatics Population-based study | No effect of inhaled corticosteroids on the decline of lung function in women compared to men | [61] |
194 asthmatics Randomized, controlled trial | Montelukast decreased the risk of worsened asthma with greater benefit in young boys and older girls | [62] |