Table 1 Local hypersensitivity reactions upon intradermal skin testing with estrogen and progesterone in patients with early recurrent pregnancy loss compared to healthy controls [18, 19]
| Study | Itsekson AM et al. Am J Reprod Immunol. 2007 [19] | Ellaithy MI et al. J Reprod Immunol. 2013 [18] | ||
|---|---|---|---|---|
| patients | controls | patients | controls | |
| Estrogen hypersensitivity | 23 | 0 | 32 | 0 |
| Progesterone hypersensitivity | 20 | 0 | 34 | 0 |
| Combined hypersensitivity | 17 | 0 | 26 | 0 |
| No hypersensitivity | 3 | 10 | 7 | 12 |
| Total numbers patients/control | 29 | 10 | 47 | 12 |