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Table 2 Comparison of particle size and lung delivery among selected inhaled corticosteroid therapies [82]

From: Small airways disease and severe asthma

Drug

Formulation

Particle size (microns)

Lung deposition

Fluticasone DPI

Dry powder

5.4 μm

15%

Fluticasone HFA

Suspension

2.4 μm

13–18%

BDP- Modulite®

Suspension

2.6 μm

36%

BDP UF-HFA

Solution

1.1 μm

>56%

Ciclesonide HFA

Solution

1–2 μm

52%

Flunisolide HFA

Solution

1.2 μm

68%

  1. BDP beclomethasone dipropionate, DPI dry powder inhaler, HFA hydrofluoroalkane, UF ultrafine
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World Allergy Organization Journal

ISSN: 1939-4551

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