Fig. 1

Lung Deposition of Beclomethasone diproprionate, Hydrofluoroalkane vs chlorofluorocarbon propellant inhaler [81]. Note the mosaic pattern of areas of low attenuation (representing air – which appears black – trapped behind diseased and functionally closed small airways) juxtaposed with areas of higher attenuation (whiter-appearing, representing lung regions from which the air has been normally expelled through patent airways)