International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem

Table 1 Allergens from Dermatophagoides species

Immunodominant		Mid-tier		Minor		Unknown
1	Cysteine protease	4	Alpha amylase	3	Trypsin	14	Large lipid transfer protein
2	ML domain protein	5	Unknown coiled coil bundle	6	Chymotrypsin	22	ML domain protein
23	Peritrophin homologue	7	LPS binding protein homologue	8	Glutathione-S-transferase	24	Cytochrome c reductase binding protein
		21	Group 5 homologue	9	Collagen serine protease	25	Triosephosphatase isomerase
				10	Tropomyosin	26	Myosin alkali light chain
				11	Paramyosin	27	Serpin
				13	Fatty acid binding	28	Heat shock protein
				16	Gelsolin	29	Cyclophilin
				17	Unknown EF hand protein	30	Ferritin
						31	Cofilin
						32	Pyrophosphatase
						33	Alpha tubulin

^aGroup 12 and 19 allergens have not been found for Dermatophagoids spp
^bNo quantitative assessments of IgE binding have been reported for the Unknown groups due to the tests used or the nature of the allergen preparations

ISSN: 1939-4551