Fig. 4

A massive infiltration and airways obstruction has been detected in the airways of a patient who died during the summer (a). The image shows a section of bronchus - hematoxylin-eosin stain - magnification × 100. Red arrow: bronchial lumen occluded by amorphous eosinophilic material corresponding to mucus plugs, mixed with inflammatory cells and epithelial cells. Green arrow: peribronchial and sub-mucosal hyperaemia, thickening of the basal membrane with muscle hypertrophy. Blue arrow: neutrophilic and limphomonocitary inflammation. The patient was sensitized to alternaria, which was detected in the airways (b); the outdoor concentration of the fungal mold was high at the time of the death