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Table 3 The proteins of cow’s milk (original source: DRACMA guidelines [1])

From: Cow’s milk allergy: towards an update of DRACMA guidelines

Fraction Protein Allergen g/L % total protein MW (kDa) # AA pIa
Caseins   Bos d 8 ~30 80    
Alphas1-casein 12–15 29 23.6 199 4.9–5.0
Alphas2-casein 3–4 8 25.2 207 5.2–5.4
Beta-casein 9–11 27 24.0 209 5.1–5.4
Gamma1-casein 1–2 6 20.6 180 5.5
Gamma2-casein     11.8 104 6.4
Gamma3-casein     11.6 102 5.8
Kappa-casein 3–4 10 19.0 169 5.4–5.6
Whey proteins    ~5.0 20    
Alpha-lactalbumin Bos d 4 1–1.5 5 14.2 123 4.8
Beta-lactoglobulin Bos d 5 3–4 10 18.3 162 5.3
Immunoglobulin Bos d 7 0.6–1.0 3 160.0 - -
BSAb Bos d 6 0.1–0.4 1 67.0 583 4.9–5.1
Lactoferrin - 0.09 traces 800.0 703 8.7
  1. aIsoelectric point
  2. bBovine serum albumin