Table 3 The proteins of cow’s milk (original source: DRACMA guidelines [1])
From: Cow’s milk allergy: towards an update of DRACMA guidelines
Fraction | Protein | Allergen | g/L | % total protein | MW (kDa) | # AA | pIa |
|---|---|---|---|---|---|---|---|
Caseins | Bos d 8 | ~30 | 80 | ||||
Alphas1-casein | 12–15 | 29 | 23.6 | 199 | 4.9–5.0 | ||
Alphas2-casein | 3–4 | 8 | 25.2 | 207 | 5.2–5.4 | ||
Beta-casein | 9–11 | 27 | 24.0 | 209 | 5.1–5.4 | ||
Gamma1-casein | 1–2 | 6 | 20.6 | 180 | 5.5 | ||
Gamma2-casein | 11.8 | 104 | 6.4 | ||||
Gamma3-casein | 11.6 | 102 | 5.8 | ||||
Kappa-casein | 3–4 | 10 | 19.0 | 169 | 5.4–5.6 | ||
Whey proteins | ~5.0 | 20 | |||||
Alpha-lactalbumin | Bos d 4 | 1–1.5 | 5 | 14.2 | 123 | 4.8 | |
Beta-lactoglobulin | Bos d 5 | 3–4 | 10 | 18.3 | 162 | 5.3 | |
Immunoglobulin | Bos d 7 | 0.6–1.0 | 3 | 160.0 | - | - | |
BSAb | Bos d 6 | 0.1–0.4 | 1 | 67.0 | 583 | 4.9–5.1 | |
Lactoferrin | - | 0.09 | traces | 800.0 | 703 | 8.7 |