Table 3 Exemplary cases of systemic reactions during skin prick test (SPT) with latex

1

SPT

Liquid latex material

Immediate flushing, tachycardia, urticaria, light-headedness

Spaner et al. 1989 [260]

34 year old female Operating room nurse

1

SPT

10 % aqueous dispersion

Cold, sweaty extremities, initial tachycardia, subsequent bradycardia, hypotension

Bonnekoh and Merk 1992 [261]

17 year old female dentist’s assistance

1

SPT

100 HEP Hevea brasiliensis

Dizziness, difficulty with breathing, wheezing, tachypnoea

Nicolaou and Johnston 2002 [262]

39 year old female house wife

6

SPT

extemporaneous extracts (dilutions of 1:1000, 1:100, and 1:10) (n = 5), commercial SPT solution (n = 1)

Signs of anaphylaxis in different degrees

Nettis et al. 2001 [48]

6 female patients with age ranging from 26-51

9

SPT

1:100,000 dilution of latex glove extract

Systemic reactions

Kelly et al. 1993 [44]

9 of 107 patients: 85 children with spina bifida, 15 health care workers, 7 others

2 or 3^a

SPT

50 % glycerine, 0.23 mg/mL total protein from gloves

Pruritus, flushing, urticaria, angioedema, asthma, cough chest tightness, wheezing, dyspnea, eye itching, nasal congestion

Valyasevi et al. 1999 [15]

2 or 3^a patients from a clinic out of 1316