From: The use of inhaled corticosteroids in pediatric asthma: update
Guideline | Last updated | Age categories (years) | Preferred step up choices after initial low dose ICS | Specifies indications for starting low dose ICS | Specifies indications for starting moderate dose ICS | Specifies indications for starting high dose ICS | Describes adverse effects | Review interval for dose drop |
---|---|---|---|---|---|---|---|---|
GINA | 2016 | Up to 5 | Mod dose ICS or add LTRA | Yes | Yes | Yes | Yes | 3 months |
 |  | 6–11 | Mod dose ICS |  |  |  |  |  |
 |  | 12 and older | Add LABA |  |  |  |  |  |
Australia | 2015 | 0–1 | NS | Yes | NS | NS | NS | NS |
 |  | 1–2 | NS |  |  |  |  |  |
 |  | 2–5 | NS |  |  |  |  |  |
 |  | 6 and older | NS |  |  |  |  |  |
Canada Preschool | 2015 | 1–5 | Mod dose ICS | Yes | Yes | NS | NS | 3 months |
Canada Older | 2012 | 6–11 | Mod dose ICS | Yes | NS | NS | Yes (CTS 2010) | weeks to months |
 |  | 12 and older | Add LABA |  |  |  |  |  |
SIGN | 2014 | 0–4 | LTRA | Yes | NS | NS | Yes | 3 months |
 |  | 5–12 | Add LABA |  |  |  |  |  |
 |  | 13 and older | Add LABA |  |  |  |  |  |
ICON | 2012 | Describes other guidelines | Describes other guidelines | NS | NS | NS | NS | NS |
Saudi Arabia (SINA) | 2012 | <5 | Mod dose ICS | Yes | NS | NS | Yes | 3–6 months |
 |  | 5 and older | Add LABA |  |  |  |  |  |
Japan | 2012 | <2 | LTRA is first choice, not ICS. Step-up: mod dose ICS | Yes | Yes | Yes | NS | 3 months |
 |  | 2–5 | Mod dose ICS |  |  |  |  |  |
 |  | 6–15 | LABA or mod dose ICS |  |  |  |  |  |
South Africa | 2009 | <5 | Mod dose ICS | Yes | NS | NS | Yes | 3 months |
 |  | 5 and older | LTRA or LABA or mod dose ICS |  |  |  |  | |
PRACTALL | 2008 | 0–2 |  | NS | NS | NS | Yes | NS |
 |  | 3–5 | Mod dose ICS or add LTRA |  |  |  |  |  |
 |  | 6 and older | Mod dose ICS or add LTRA |  |  |  |  |  |
NHLBI | 2007 | 0–4 | Mod dose ICS | Yes | NS | NS | Yes | 3 months |
 |  | 5–11 | Mod dose ICS or add LABA |  |  |  |  |  |
 |  | 12 and older | Add LABA |  |  |  |  |  |
India | 2003 | <5 | Mod dose ICS | Yes | NS | NS | Yes | 3–6 months |
 |  | 5 and older | Add LABA |  |  |  |  |  |