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Table 3 Main current diagnostic procedures for allergy/hypersensitivity (adapted from [48])

From: Dissemination of definitions and concepts of allergic and hypersensitivity conditions

IgE-mediated hypersensitivity diagnostic procedures T-Lymphocyte-mediated hypersensitivity diagnostic procedures
In vitro
 − Serum allergen specific-IgE
 − Serum (or plasma) tryptase
 − Basophil activation test (BAT)
 − Cellular Antigen Stimulation Test (CAST)- Enzyme linked ImmunoSorbent Assay (ELISA)
In vitro
 − Lymphocyte transformation blood test
 − Enzyme-Linked ImmunoSpot (ELISPOT)
 − CD69 expression
In vivo
 − Skin tests
  • Skin prick tests
  • Intradermal skin tests
 − Provocation test
In vivo
− Skin tests
  • Skin patch tests/Photopatch tests
  • Intradermal skin tests
− Provocation test