Table 1 Cellular expression profiles of FcεRI isoforms in humans and wild type mice. Composition of the tetrameric isoform: IgE binding alpha chain, beta and the gamma dimer. Alpha chain contains the IgE binding site. Beta and gamma are the signal transducing subunits. Composition of the tetrameric isoform: IgE binding alpha chain and the gamma dimer. For review see also [96, 107]. Note that only a minor fraction of eosinophils in esophageal tissue of EoE patients expresses FcεRI [97]

From: Eosinophilic esophagitis: published evidences for disease subtypes, indications for patient subpopulations, and how to translate patient observations to murine experimental models