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Table 4 Tryptase levels in relation to mastocytosis amd anaphylaxis

From: Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

Condition

Serum total tryptase level (ng/ml)

Comments

Healthy

1–11

Level is primarily genetically determined

Mastocytosis

>20

Levels <20 do not rule out mastocytosis, particularly in patients who have had systemic anaphylaxis to an insect sting

Anaphylaxis

>[2 + (1.2*baseline level)]

Acute serum within 4 h of event onset; baseline serum either before acute event or >24 h after all signs and symptoms resolve