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Table 4 Tryptase levels in relation to mastocytosis amd anaphylaxis

From: Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

Condition Serum total tryptase level (ng/ml) Comments
Healthy 1–11 Level is primarily genetically determined
Mastocytosis >20 Levels <20 do not rule out mastocytosis, particularly in patients who have had systemic anaphylaxis to an insect sting
Anaphylaxis >[2 + (1.2*baseline level)] Acute serum within 4 h of event onset; baseline serum either before acute event or >24 h after all signs and symptoms resolve