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Table 2 Tolerance of baked egg and resolution of egg allergy

From: Debates in allergy medicine: baked milk and egg ingestion accelerates resolution of milk and egg allergy

 

Type of study

BE tolerant

Resolution of egg allergy

Sicherer et al. [40] (n = 113)

Observational without OFC

38 % by 6 years

After 6 years:

71 % in those who reported BE tolerance

45 % in those not ingesting BE

57 % in those who reported BE reactivity

Des Roches et al. [30]

Prospective with OFC

73 %

 

Lemon-Mule et al. [19] (n = 91) and Leonard et al. [31] (n = 79; follow-on study)

Prospective with OFC

70 % initially,

53 % of those ingesting BE (followed for median 37.8 months)

89 % by end of follow-on study

28 % of control group (followed for median 67.3 months)

Clark et al. [24] (n = 95)

Longitudinal with OFC

66 %

N/A

Lieberman et al. [25] (n = 100)

Retrospective with OFC

66 %

N/A

Cortot et al. [26] (n = 52)

Retrospective with OFC

83 %

N/A

Turner et al. [18] (n = 236)

Prospective with OFC

64 %

N/A

Tan et al. [27] (n = 143)

Prospective with OFC

63 %

N/A

Bartnikas et al. [28] (n = 169)

Retrospective with OFC

84 %

N/A

Turner et al. [29] (n = 186)

Retrospective with OFC

66 %

N/A

Peters et al. [37] (n = 158)

Prospective with OFC or by report

80 % by OFC

By age 2 years of age:

72 % by report

49 % of those ingesting BE after OFC at 1 year

74 % of those ingesting BE by report at 1 year

13 % of those with positive BE OFC at 1 year

  1. OFC oral food challenge, BE baked egg