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Table 3 Clinical phenotypes and allergen sensitization at 2 years as risk factors for atopic outcomes at 5 years

From: Clinical phenotype and allergen sensitization in the first 2 years as predictors of atopic disorders at age 5 years

Allergic phenotypes

  

5 years

Phenotype risk factors at 2 years

Adjusted OR (95 % CI) **

Eczema

No eczema, wheeze, rhinitis and allergen sensitization (n = 110) a

1

n = 26

Allergen sensitization only (n = 16)

4.0 (0.6–27.5)

 

Eczema only ( n = 32) *

7.1 (1.8–27.8)

 

Wheeze only (n = 32)

0.7 (0.1–7.2)

 

Eczema and allergen sensitization ( n = 12) *

25.4 (4.7–138.5)

 

Wheeze and allergen sensitization (n = 4)

9.6 (0.6–142.4)

 

Eczema and wheeze (n = 3)

28.3 (1.0–814.9)

 

Eczema, wheeze and allergen sensitization ( n = 5) *

64.9 (4.7–900.0)

Wheeze

No eczema, wheeze, rhinitis and allergen sensitization (n = 110) a

1

n = 32 b

Allergen sensitization only (n = 16)

1.9 (0.3–10.4)

 

Eczema only (n = 32)

1.4 (0.4–5.5)

 

Wheeze only ( n = 32)

4.5 (1.4–14.8)

 

Eczema and allergen sensitization (n = 12)

3.1 (0.6–15.7)

 

Wheeze and allergen sensitization (n = 4)

7.8 (0.8–71.2)

 

Eczema and wheeze (n = 3)

20.9 (0.9–499.6)

 

Eczema, wheeze and allergen sensitization (n = 5)

13.9 (1.2–168.5)

 

Eczema, rhinitis and allergen sensitization (n = 2)

16.5 (0.8–360.2)

Rhinitis

No eczema, wheeze, rhinitis and allergen sensitization (n = 110) a

1

n = 32 b

Allergen sensitization only ( n = 16)

5.6 (1.1–29.2)

 

Eczema only ( n = 32) *

6.8 (2.0–23.1)

 

Wheeze only (n = 32)

1.7 (0.4–7.9)

 

Eczema and allergen sensitization (n = 12)

3.8 (0.7–20.6)

 

Eczema, wheeze and allergen sensitization (n = 5)

10.1 (1.0–104.1)

Allergen sensitization

No eczema, wheeze, rhinitis and allergen sensitization (n = 110) a

 

n = 111

Allergen sensitization only ( n = 16) *

9.0 (2.3–35.3)

 

Eczema only ( n = 32) *

3.6 (1.5–8.7)

 

Wheeze only (n = 32)

1.1 (0.4–2.7)

  1. Statistically significant variables (p < 0.05) highlighted in bold and (p < 0.01) variables highlighted in bold and marked with *
  2. ** indicates adjusted for other variables (such as probiotic supplementation, gender, ethnic group, mode of delivery, maternal atopy, paternal atopy, sibling atopy and IgE measurements at 1 year) in the table that were selected based on the univariate analysis and a p value of <0.1
  3. a indicates the reference group
  4. b indicates missing SPT