Table 4 Steps for the evaluation framework of biomarkers
From: Allergen Immunotherapy (AIT): a prototype of Precision Medicine
• Analytical validation of reliability, reproducibility, and adequate sensitivity and specificity. |  |
• Qualification to ensure that the biomarker is associated with the clinical outcome including prognosis. |  |
• Utilisation analysis to determine that the biomarker is appropriate for the proposed use. |  |