Figure 1

Enrollment and outcome. 505 patients were enrolled for eligibility out of which only 192 fulfilled the eligibility criteria. 276 patients did not fulfill the criteria, 18 patients refused to participate, 8 withdrew before treatment, 4 patients having evidence of current drug/alcohol abuse were not recruited for the study and 7 did not show up after screening. 192 patients fulfilling the eligibility criteria were randomized into groups a, b and c. 48 patients in group a, 42 in group b and 57 in group c completed the study. The rest withdrew from study, had adverse events, missed to take the dose, were withdrawn by the guardian or were lost to follow-up.