From: The care pathway for children with urticaria, angioedema, mastocytosis
HAE 1 | Low production of functionally active C1-INH |
HAE 2 | Normal or elevated levels of C1-INH, but with functional impairment of the protein |
HAE3 (irrelevant in children and adolescent) | Mutations in the coagulation factor XII. No abnormalities in C1-INH level or function |