Skip to main content


We’d like to understand how you use our websites in order to improve them. Register your interest.

Clinical and laboratorial aspects of hens egg allergy in childhood


The prevalence of hen´s egg allergy is estimated in 0.5 to 2.5 per cent of young children. In view of this, clinical and laboratory aspects of hen´s egg allergy were assessed in children at a specialized clinic.


Prospective study conducted from 1997 to 2014 in children at the age of 0 to 18 years old with hen´s egg allergy. Eosinophilia was considered over 400 cells / mm ³. The technique used for specific IgE was immunofluorescence. The result of prick test was the average of the papule, considered positive papules over 3mm. The results were presented as mean values.


It was evaluated 159 children, with 58.5% male. The mean age at diagnosis was 1 year and 11 months old. Among the patients followed 25.1% achieved oral tolerance, and this was achieved after 1 year and 10 months of diagnosis. The clinical manifestations evaluated were: atopic eczema (27.0%), urticaria (24.5%), atopic eczema associated with urticaria (13.2%), anaphylaxis (8.8%), gastrointestinal tract manifestations (8.8%), respiratory tract manifestations (8.8 %), urticaria and angioedema (7.5%) and angioedema (1.8%). The following laboratory aspects evaluated were: Eosinophilia was present in 30.1% of patients. The mean total IgE was 1108.8 IU/ml. The specific IgE to hen´s egg was 9.3 IU/ml and to the allergenic component ovomucoide was 1.9 IU/ml. The mean wheal to hen´s egg in prick test was 4.8mm.


It was concluded that allergy to hen´s egg was more common in males. The opportune diagnosis of allergy to hens egg was considered late, on the other hand, oral tolerance was achieved rapidly. The most common clinical manifestation was atopic eczema and mean total IgE was elevated.

Author information



Corresponding author

Correspondence to Eliana Toledo.

Rights and permissions

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Toledo, E. Clinical and laboratorial aspects of hens egg allergy in childhood. World Allergy Organ J 8, A85 (2015).

Download citation