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World Allergy Organization Journal

Open Access

The prevalence of causes of cell mediated food allergy in children in Rio de Janeiro

  • Isaac Azevedo Tenorio1,
  • Aderbal Sabra1 and
  • Selma Sabra1
World Allergy Organization Journal20158:794

Published: 8 April 2015


The frequency of Food Allergy (FA) has been increasing in recent years. The prevalence of cell-mediated FA among this cases is unknown. The major cause for the difficulty of this diagnosis of cell-mediated FA is the absense of a major biomarquer. In this study we select patients with cell-mediated FA based in their Clinical Picture, normal IgE and clinical cure with the treatment with the withdrow of the offending food from the diet.

Material and methods

71 patients were selected for the study, with cell-mediated FA. In this group of patients we caracterise their clinical picture.


The clinical diagnosis among all the 71 patients studied was: in 62% (44 patients) the clinical diagnosis was Cow’s Milk Enteropathy (CME); in 15.5% (11 patients) the clinical diagnosis was Breast Milk Colitis (BMC); in 8.45% (6 patients) the clinical diagnosis was Abdominal Pain and Abdominal Distention with Motor Impairment (APAD); in only 5.6% (about 4 patients) the clinical diagnosis was Cow’s Milk Enterocolitis( FPIES); in others 5.6% (4 patients) the clical diagnosis was Constipation (C) and finaly in 2.8% (in 2 patients) the clinical diagnosis was Celiac Disease.


The highest prevalence among all cases of FA cell ltype mediated was CME, the second clinical picture in frequency was BMC. Less frequent causes of cell mediated FA in Rio de Janeiro was APAD, FPIES, C and CD.

Authors’ Affiliations

Unigranrio, Brazil


© Tenorio et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.