Skip to main content
Download PDF

Volume 8 Supplement 1

3rd WAO International Scientific Conference (WISC) 2014

  • Meeting abstract
  • Open access
  • Published:

Serum total IgE, ascaris lumbricoides specific IgE and eosinophils in parasites-infected children in a tropical area

World Allergy Organization Journal volume 8, page A223 (2015)Cite this article

Background

This study investigated the relationship between total IgE and Ascaris lumbricoides specific IgE and eosinophils in children from endemic areas to assess the Th2-type immune response in a population that comprised 205 children with aged 1-10 years, and of low socioeconomic status.

Methods

Fecal samples were analysed by the methods of Blagg and Kato-katz. The serum levels of total IgE and A. lumbricoides specific IgE were determinated by ImmunoCAP (Pharmacia) and the eosinophils were counted in peripheral blood.

Results

The results showed a prevalence of 89% (182) for intestinal parasites. A. lumbricoides was detected in 140 (68%) children. The levels of total and specific IgE and eosinophils presented values above those of standard reference (median 480 KU/L and 0,74 KUA/L and 8%, respectively). Total IgE, A. lumbricoides specific IgE and eosinophils were significantly higher in the A. lumbricoides positive children as compared to A. lumbricoides negative ones (p = 0.02, <0.01 and 0.03).

Conclusions

Our results showed that parasites intestinal infection, particularly A. lumbricoides, induced a Th2-type immune response with production of the total and specific IgE and eosinophils.

Author information

Authors and Affiliations

  1. Federal University of Rio Grande Do Norte, Brazil

    Valéria Soraya De Farias Sales, Edna Marques Araújo Silva, Sarah Dantas Viana Medeiros, Luanda Bárbara Ferreira Canário Souza, Vanessa Marques Araújo Silva, Tereza Neuma De Souza Brito & Paula Renata Lima Machado

Authors
  1. Valéria Soraya De Farias Sales
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Edna Marques Araújo Silva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Sarah Dantas Viana Medeiros
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Luanda Bárbara Ferreira Canário Souza
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Vanessa Marques Araújo Silva
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Tereza Neuma De Souza Brito
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Paula Renata Lima Machado
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

De Farias Sales, V.S., Silva, E.M.A., Medeiros, S.D.V. et al. Serum total IgE, ascaris lumbricoides specific IgE and eosinophils in parasites-infected children in a tropical area. World Allergy Organ J 8 (Suppl 1), A223 (2015). https://doi.org/10.1186/1939-4551-8-S1-A223

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/1939-4551-8-S1-A223

World Allergy Organization Journal

ISSN: 1939-4551

Contact us