Skip to main content


We’d like to understand how you use our websites in order to improve them. Register your interest.

Epidemiological survey on the practice of allergen immunotherapy in Brazil


Allergen immunotherapy (IT) is widely used to treat patients with allergic diseases, proven effective and recommended by national and international guidelines. Its efficacy and safety depend on the correct indication, use of relevant allergens and good quality extracts, as well as prescription and supervision by a trained professional. Our aims were to evaluate the frequency of use of IT in Brazil and to investigate whether this practice meets recommendations of the Brazilian Association of Allergy and Immunology (ASBAI) and Brazilian Medical Association.


Standardized questionnaire consisting of 20 items was applied to physicians participating in the annual congress of ASBAI. The questionnaire was anonymous and voluntary, and evaluated data related to medical training, board certification, duration of professional practice, indications for IT, age limitation, mode of administration and schedules, type and standardization of extracts, duration of IT and administration site.


Four-hundred twenty two questionnaires were completed; 88.2% of participating professionals reported training in Allergy and Immunology, and 57.8% were Board certified in Allergy and Immunology. Sixty-eight percent practice the specialty >5 years; 79.2% work in private practice and 80.6% perform IT in clinical practice. Among IT prescribers, 121 (35.6%) are not Board certified by ASBAI. IT is used most often with the following indications: rhinoconjunctivitis - 97.9%, cutaneous reactions to mosquito bites - 75.1%, asthma - 72.2%, atopic dermatitis - 57.4%, allergy to insect stings - 52.1% and food allergy - 7.9%. The data revealed that 75.6% of professionals prescribe IT for children <5 years and 48.2% for patients> 65 years. Mode of IT included SCIT - 91.7%; SLIT - 52.9%; SCIT rush - 7.1% and oral desensitization - 10.9%. The duration of IT was: <3 years - 38.7%, 3-5 years - 58% and> 5 years - 1.2%. IT is conducted in health care units in 88.1% of cases.


Both SCIT and SLIT are widely used in Brazil. Most professionals who use IT have training in Allergy and Immunology (88.2%), however, only 57.8% are Board certified. The practice of IT occurs predominantly in private clinics. A significant percentage of physicians perform practices which are not in full agreement with national and international recommendations, including prescription of IT for children <5 years and patients > 65 years, and duration of IT less than 3 years in 38.7% of cases.

Author information



Corresponding author

Correspondence to José Luiz De Magalhães Rios.

Rights and permissions

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

De Magalhães Rios, J.L., Rubini, N., Cohon, A. et al. Epidemiological survey on the practice of allergen immunotherapy in Brazil. World Allergy Organ J 8, A189 (2015).

Download citation