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World Allergy Organization Journal

Open Access

Chronic urticaria: the first visit in a specialized unit

  • Camila Teles Machado Pereira1,
  • Barbara M Aquino1,
  • Fernanda Cabral Cardoso Hardt1,
  • Luis Felipe Ensina1,
  • Inês Cristina Camelo Nunes1 and
  • Dirceu Sole2
World Allergy Organization Journal20158:637

Published: 8 April 2015


The aim of this study was to evaluate the clinical profile of patients with chronic urticaria (CU) at first visit in a specialized CU unit.


Cross-sectional study of patients seen from January/2012 to June/2014. Patients diagnosed with acute urticaria (n=5) were excluded.


Among the 50 CU patients, 70% were female. The mean age at the consultation was 33 years, but the mean age of symptoms onset was 15.3 years. Fifty one percent referred only urticaria, 44% referred urticaria associated with angioedema and 5% presented isolated angioedema. Besides itching, 6 patients complained of burning (12%) and 2 of pain (4%). Frequency of wheals was daily in 33%, weekly in 36% and monthly in 31%. At first visit, Urticaria Activity Score was verified in 24 patients, resulting > 3 in half of them. The most associated atopic disease was rhinitis (45%). Many patients mentioned triggers as medicines (33%), food (23%), stress (17%), viral infection (8%) and physical agents (16%). Only 6% had thyroidopathy. As previous treatment a significant amount of patients received sedating antihistamines (AH) (36%) or oral corticosteroids (24%), with partial improvement in 65% and complete improvement in 29%. Dermographism was positive in 91% of the patients tested (20/22). One of them was diagnosed with cholinergic urticaria and another one with delayed pressure urticaria.


The higher prevalence of CU was in middle-aged women. However, strong association with thyroiditis was not found. Sedating AH and corticosteroids are still the most prescribed drugs.

Authors’ Affiliations

Federal University of Sao Paulo, Brazil
Brazilian Society, Brazil


© Machado Pereira et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.