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Table 6 Characteristics of the SLIT-induced anaphylaxis reported in literature

From: Sublingual immunotherapy: World Allergy Organization position paper 2013 update

Author, year [reference]

Sex (age)

Allergen (producer)

Phase

Onset

Description

Epinephrine

De Groot, 2009 [79]

M (13)

Grass (Grazax, ALK-Abellò)

First dose

15 min

Generalized urticaria, swelling of tongue

No

De Groot, 2009 [79]

F (27)

Grass (Grazax, ALK-Abellò)

First dose

5 min

Abdominal cramps, asthma, generalized itching, hypotension

Yes (SC)

Blazowski, 2008 [80]

F (16)

HDM (Staloral, Stallergenes)

Maintenance overdose (60 drops)

10 min

Hypotension-collapse, flushing, urticaria

Yes (IM)

Eifan, 2007 [81]

F (11)

Mixture (dust mite + grass pollen mix (Stallergenes)

Maintenance

3 min

Abdominal pain, chest pain, fever, nausea

Not specified

Dunsky, 2006 [82]

F (31)

Alternaria, cat, dog grass, ragweed, (Greer)

2nd day of updosing

5 min

Angioedema, dizziness, dyspnea, generalized itching

No

Antico, 2006 [83]

F (36)

Latex

End of rush buildup

10 min

Asthma, generalized urticaria

Not specified

  1. SC: subcutaneous IM: intramuscular.