Table 2 Pros and cons for prescribing auto-injectable epinephrine for SLIT
From: Current status of sublingual immunotherapy in the United States
Pros | Cons |
|---|---|
● There is a slight, though rare risk for anaphylaxis. | ● Adverse reactions with SLIT are generally mild, and systemic reactions are generally not severe, with no deaths reported. |
● SLIT is a home-based therapy without anaphylaxis-trained practitioners available should a reaction occur | ● Auto-injectable epinephrine may be used incorrectly or inappropriately by patients. |
● There are medical-legal concerns if a patient should have a reaction at home without having an auto-injector prescribed. | ● Auto-injectors are not required for SLIT in Europe and Canada. Many US practitioners do not require them for SCIT patients. |
● Costs of epinephrine autoinjectors |