Table 2 Data used or calculated by the inference engine (IE)

1) Single components, such as Der p 1 or Der p 2, in ISU.

2) Single source allergens, corresponding to the sum of the components, such as Der f 1 and Der f 2 for Dermatophagoides pt.

3) Comprehensive source allergens (such as Der f 1, Der f 2 and Der p10 – a component highly homologous to the Der f 10 that is not included in the ISAC panel).

4) Cross-reactive families (such as tropomyosins, represented by Ani s 3, Bla g 7, Der p 10 and Pen m 1), as well as PR-10 and profilins, among others.

5) Allergen groups (such as mites, grasses and trees), represented by the sum of the score of the components belonging to those groups.

6) Enlarged component groups (such as inhalants, food, latex and Hymenoptera venoms), represented by the sum of the score of the components belonging to those large groups.

7) The total amounts of the scores for either genuine or cross-reactive inhalant components are also calculated to support the patient’s phenotyping.