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World Allergy Organization Journal

Open Access

Allergic diseases of the skin and drug allergies – 2012. Is there association between duration of seasonal alleric rhinitis and oral allergy syndrome?

  • Reza Faridhosseini1,
  • Farahzad Jabbari1,
  • Afshin Shirkani1,
  • Mohammad Reza Zandkarimi1 and
  • Hadis Yousefzadeh1
World Allergy Organization Journal20136:383

Published: 23 April 2013


PlaceboCross Sectional StudyDemographic DataRhinitisFood Allergy


Oral allergy syndrome (OAS) characterized by oral IgE-Mediated symptoms, which is caused by cross-reactivity between proteins in pollen and fresh fruit or vegetables .Association between oral allergy syndrome and duration of seasonal allergic rhinitis, is not well known.


In this cross sectional study, 103 consecutive patients with seasonal allergic rhinitis were enrolled. Sensitization to common aeroallergen confirmed by skin prick test 3 millimeter more than negative control. Clinical symptoms, personal and familial history of atopy and demographic data were listed. According to food allergy history 63 of 103 patients had positive Open Single-Blind Oral Food Challenge Test that was associated with oral allergy syndrome.


Among studied cases, 63 patients (61.2%) with 28.8±10.6 years old had OAS and 40 (38.8%) with 26.8±13.2 years had not OAS. We found that duration of seasonal allergic rhinitis in OAS group (7±5.9 years old) and non OAS group (5±4 years ) was significantly correlated (P=0.03).


In this study, duration of seasonal allergic rhinitis was associated significantly with oral allergy syndrome. However further studies with more sample sizes and double blind placebo methods might be need.

Authors’ Affiliations

Mashhad University of Medical Science, Mashhad, Iran


© Faridhosseini et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.