Rhinitis, sinusitis and ocular disease – 2092. The MSNOT-20 questionnaire: repeatability and disease analysis of rhinitis/rhinosinusitis
© Sami et al; licensee BioMed Central Ltd. 2013
Published: 23 April 2013
Sinonasal disease is prevalent and impacts on quality of life, the Modified SNOT-20 (MSNOT-20) questionnaire aims to provide a complete assessment of rhinitis/rhinosinusitis and its impact. Following a pilot study evaluation, the main project assessed the prevalence of rhinitis/rhinosinusitis in a community based survey in Farnborough, UK. A sub group was invited for clinical examination and repeatability of MSNOT-20.
Further repeatability was carried out through a study of self-referral patients to the ENT department of Services Hospital, Lahore, Pakistan. This study aimed to obtain the current burden of rhinitis/rhinosinusitis in these patients and subsequent disease course.
Following a successful pilot study comparing disease with non-disease, 2000 postal questionnaires were sent to randomly selected adults. A sub group of the sample was invited to the hospital for clinical examination and for the repeatability of MSNOT-20.
The Lahore study looked at 200 patients who completed the MSNOT-20 questionnaire on initial presentation and, over the course of 3 consultations, were assessed for disease response to provided therapy by completing MSNOT-20 at each point. For unresponsive cases to conventional therapy, blood tests were used to identify the aetiology of disease.
The pilot project showed significant differences (p<0.001) between disease and non-disease. Analysis of responses allowed a discriminating score of ≥2 (on a 0-5 scale) being an abnormal response. The Farnborough study identified 32% of respondents (79.8% response rate) as disease with significant correlations between disease domain and the 4 other domains (paranasal [sinus and ear], sleep, social and emotional).
Analysis of the Lahore study found 25% of the self-referral population suffered from rhinitis /rhinosinusitis, 5% of patients had a form of surgical intervention ranging from antral wash out to endoscopic sinus surgery, 2% had associated pathologies in the form of deflected nasal septum, nasal polyp or antrochoanal polyp.
MSNOT-20 questionnaire has identified a high prevalence of nasal and paranasal problems within the community and in self referrals with significant associated co-morbidity. The MSNOT-20 has proven to be a valid, reliable and repeatable disease specific quality of life questionnaire able to evaluate the presence, severity and assessment of response to treatment.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.