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Allergic diseases of the skin and drug allergies – 2032. Epidemiological study of a specific unit of drug allergy diagnosis - 20 years experience
World Allergy Organization Journal volume 6, page P118 (2013)
To determine the allergy incidence to drugs in patients visited in our unit with a clinical history suggestive of allergic hypersensitivity to one or more drugs. Our area of influence is the whole region of Catalonia, North-East of Spain.
We use our own method of diagnosis; keeping in mind the limitations in our medical practice such as a difficult anamnesis; few standardised skin tests for most substances; and the scarce reliability of the in-Vitro tests. The provocation test was the gold standard of the definitive diagnosis.
33750 patients have been studied in 20 years; each patient has undergone an average of 1.4 tests 68% of them being female and 32% male.
A positive result was found in 20% of the studied cases; 8% of these related to placebo. The most studied drugs have been the beta lactamates (50%), non-steroid anti-inflamatories (NSAIDs) (30%), local anesthesics (10%), others (10%).
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Marti, E., Scorza, E. Allergic diseases of the skin and drug allergies – 2032. Epidemiological study of a specific unit of drug allergy diagnosis - 20 years experience. World Allergy Organ J 6, P118 (2013). https://doi.org/10.1186/1939-4551-6-S1-P118
- Positive Result
- Epidemiological Study
- Gold Standard