Association between autoimmune reactions and severity of atopic dermatitis in children with herpes virus infection

Table 5 The levels and frequency of detection of IgG-abs to herpes viruses in sera of children of school age

Severity of AD	Amount of patients	Antigens	Levels of IgG-abs		Frequency of occurrence of IgG-abs in patients, %
Severity of AD	Amount of patients	Antigens	Cut-off (in HV-negative people)	In children with AD, Me (QR)	Frequency of occurrence of IgG-abs in patients, %
Mild	16	HSV	0.223	0.19 (2.68)	43.75
		CMV	0.2	6.07* (6.13)	93.75
		EBV	0.45	2.75* (0.57)	87.5
Moderate	14	HSV	0.223	0.21 (2.65)	50
		CMV	0.2	4.59* (5.67)	92.86
		EBV	0.45	2.63* (1.82)	92.86
Severe	24	HSV	0.223	2.93* (3.01)	70.83
Severe	24	CMV	0.2	1.35* (5.48)	91.67
		EBV	0.45	2.04* (2.45)	91.67

The levels of IgG-abs to HSV and EBV are in units of OD. The levels of IgG-abs to CMV are in ЕР/ml.
* – valid differences in the levels of IgG-abs to herpes viruses between children with AD and HV-negative people (p < 0.05).

ISSN: 1939-4551