Association between autoimmune reactions and severity of atopic dermatitis in children with herpes virus infection

Table 4 The levels and frequency of detection of IgG-abs to herpes viruses in sera of children of preschool age

Severity of AD	Amount of patients	Antigens	Levels of IgG-abs		Frequency of occurrence of IgG-abs in patients, %
Severity of AD	Amount of patients	Antigens	Cut-off (in HV-negative people)	In children with AD, Me (QR)	Frequency of occurrence of IgG-abs in patients, %
Mild	23	HSV	0.223	0.169 (1.28)	34.78
		CMV	0.2	0.39* (3.72)	91.3
		EBV	0.45	2.19* (1.37)	95.65
Moderate	41	HSV	0.223	0.173 (2.53)	46.34
		CMV	0.2	1.2* (5.43)	92.68
		EBV	0.45	2.59* (0.98)	92.68
Severe	39	HSV	0.223	0.23 (2.81)	51.28
Severe	39	CMV	0.2	2.43* (5.24)	89.74
		EBV	0.45	0.86* (1.87)	92.31

The levels of IgG-abs to HSV and EBV are in units of OD. The levels of IgG-abs to CMV are in ЕР/ml.
* – valid differences in the levels of IgG-abs to herpes viruses between children with AD and HV-negative people (p < 0.05).

ISSN: 1939-4551