Table 3 The levels and frequency of detection of IgE- and IgG-abs to tissue antigens in children of school age with AD
Severity of AD | Amount of patients | Levels of total IgE KU/l | Antigens | Cut-off | Level of abs (QR) to tissue antigens | Frequency of occurrence of abs, % | |||
|---|---|---|---|---|---|---|---|---|---|
IgE-abs МЕ/ml | IgG-abs μg/ml | IgE-abs МЕ/ml | IgG-abs μg/ml | IgE-abs | IgG-abs | ||||
Mild | 16 | 19 (36) | Keratin | 1.48 | 206 | 1.7 (4.68)* | 209.8 (213.5)* | 50* | 68.8* |
Collagen VI | 1.4 | 49 | 1.4 (1.2) | 82.5 (156.1)** | 31.3 | 62.5 | |||
Elastin | 1.4 | 25 | 1.4 (1.07)* | 25 (56.8) | 43.8* | 31.3 | |||
Collagen III | 1.4 | 54 | 1.4 (0.71) | 45.2 (77.5) | 31.3 | 43.8 | |||
Myosin | 3.1 | 200 | 1.87 (9.5) | 25 (140.5) | 43.8 | 18.8 | |||
Moderate | 14 | 72 (133) | Keratin | 1.48 | 206 | 1.87 (1.5) | 281.1 (90.5)** | 57.1 | 71.4 |
Collagen VI | 1.4 | 49 | 1.4 (0.05) | 59.1 (49.4) | 28.6 | 57.1 | |||
Elastin | 1.4 | 25 | 1.48 (1.0) | 38.3 (104.5) | 57.1 | 50 | |||
Collagen III | 1.4 | 54 | 1.4 (−) | 50.9 (70.8) | 21.4 | 42.9 | |||
Myosin | 3.1 | 200 | 1.4 (1.92) | 136.6 (147) | 28.6 | 21.4 | |||
Severe | 24 | 128 (471) | Keratin | 1.48 | 206 | 2.71 (12.29)* ** | 296.2 (214.1) * ** | 62.5* | 75* |
Collagen VI | 1.4 | 49 | 1.4 (−) | 25 (18.3) | 4.2 | 29.2 | |||
Elastin | 1.4 | 25 | 2.69 (1.38)* ** | 25 (10.7) | 58.3* | 29.17 | |||
Collagen III | 1.4 | 54 | 1.4 (−) | 25 (33.5) | 8.3 | 29.2 | |||
Myosin | 3.1 | 200 | 1.4 (−) | 40.29 (60.2) | 8.3 | 16.7 | |||