Table 2 Diagnoses and classification of rhino-conjunctivitis (RC) and asthma by treatment modality at baseline (B) and at follow-up (F) with an intension to treat approach N = 248
Grass pollen only N = 169 | House dust mites(HDM)only N = 25 | Grass and HDM mites N = 54 | Full sample N = 248 | P-value | |||||
|---|---|---|---|---|---|---|---|---|---|
B | F | B | F | B | F | B | F | ||
RC diagnosis, ± classification | |||||||||
RC diagnosis | 169 | 166 | 25 | 23 | 54 | 48 | 248 | 237 | |
No RC diagnosis | 0 | 3 | 0 | 2 | 0 | 6 | 0 | 11 | 0,013 a |
Intermittent RC | 7 | 57 | 4 | 8 | 4 | 18 | 15 | 83 | |
Persistent RC | 162 | 109 | 21 | 15 | 50 | 30 | 233 | 154 | |
Asthma diagnosis | |||||||||
Asthma diagnosis | 81 | 70 | 12 | 8 | 28 | 24 | 121 | 102 | < 0.001a |
No asthma diagnosis | 88 | 99 | 13 | 17 | 26 | 30 | 127 | 146 | |
Intermittent | 29 | 27 | 6 | 3 | 7 | 8 | 42 | 38 | |
Mild Persistent | 21 | 22 | 1 | 1 | 6 | 3 | 28 | 26 | |
Moderate Persistent | 28 | 18 | 4 | 3 | 11 | 12 | 43 | 33 | |
Severe Persistent | 3 | 3 | 1 | 1 | 4 | 1 | 8 | 5 | |
Days with inconvenience last year mean (SD) | 160.2 (105.1) | 119.6 (118.5) | 270.9 (102.8) | 191.1 (137.6) | 247.2 (134.0) | 185.3 (142.8) | 189.3 (119.9) | 141.1 (123.4) | < 0.001b |
Sick-days last year mean (SD), ‘median, min- max days’ | 3.49 (17.78) ´0, 0-220` | 0.88 (3.04)´ 0, 0–22.5` | 6.75 (13.72) ´0, 0-55` | 4.00 (12.51) ´0, 0-55` | 2.87 (6.05) ´0, 0-30` | 0,87 (2.30) ´0, 0-10` | 3.68 (15.58) ´0, 0-220` | 1.19 (4.82) ´0, 0-55` | < 0.001b |
HRQoL- scores mean (SD) | |||||||||
RQLQ* | 3.12 (0.68) | 2.01 (0.78) | 3.21 (0.66) | 2.34 (0.76) | 2.61 (0.79) | 1.83 (0,85) | 3.02 (0.74) | 2.00 (0.80) | < 0.001b |
EQ-5D-score on days with no allergen exposure | 0.98(0.06) | 0.98 (0.07) | 0.93 (0.13) | 0.97 (0.08) | 0.98 (0.05) | 0.99 (0.04) | 0.98 (0.07) | 0.98 (0.07) | 0.975 |
EQ-5D-score on days with allergen exposure | 0.70 (0.18) | 0.78 (0.15) | 0.60 (0.30) | 0.67 (0.27) | 0.72 (0.18) | 0.80 (0.15) | 0.70 (0.20) | 0.77 (0.17) | < 0.001b |
15D-score on days with no allergen exposure | 0.98 (0.03) | 0.98 (0.04) | 0.97 (0.05) | 0.97 (0.05) | 0.98 (0.03) | 0.99 (0.02) | 0.98 (0.03) | 0.98 (0.04) | 0.180 |
15D-score on days with allergen exposure | 0.83 (0.08) | 0.86 (0.08) | 0.79 (0.09) | 0.81 (0.11) | 0.83 (0.08) | 0.88 (0.07) | 0.83 (0.08) | 0.86 (0.08) | < 0.001b |