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Table 3 Changes of the RQLQ Domains at 4 Weeks From Baseline

From: Persistent Allergic Rhinitis and the XPERT Study

 

Placebo Change

Levocetirizine (5 mg) Change

Difference versus Placebo (95% CI)

Domain

N*

Adjusted Mean† (SEM)

N*

Adjusted Mean† (SEM)

Adjusted Mean

P

Activities

241

−1.36 (0.10)

248

−2.08 (0.10)

0.73 (0.47-0.99)

<0.001

Emotions

252

−0.81 (0.07)

257

−1.16 (0.07)

0.35 (0.17-0.54)

<0.001

Eye symptoms

252

−0.91 (0.09)

257

−1.40 (0.09)

0.48 (0.26-0.70)

<0.001

Non-hay fever symptoms

252

−0.83 (0.08)

257

−1.21 (0.08)

0.38 (0.18-0.57)

<0.001

Nasal symptoms

252

−1.10 (0.09)

257

−1.64 (0.09)

0.54 (0.31-0.77)

<0.001

Practical problems

252

−1.50 (0.10)

257

−2.06 (0.10)

0.56 (0.30-0.82)

<0.001

Sleep

252

−0.86 (0.09)

257

−1.35 (0.09)

0.50 (0.27-0.73)

<0.001

  1. *Number of ITT patients with nonmissing values at baseline and under treatment.
  2. †Mean change from baseline, adjusted for baseline score and country.