Figure 2

Comparison of TLR4-mediated responses in neonates at high and low risk of allergy (based on maternal allergy): interferon-γ and IL-12 responses were measured after stimulation with TLR4 ligand (LPS). The cytokine levels in culture supernatants (picograms per milliliter) after 48 hours are displayed as median, and 5, 25, 75, and 95 percentile ranges and outlying values. All responses are shown as the levels in stimulated cultures after subtracting levels in the unstimulated control cultures. Data from high-risk neonates (shaded bars) were compared with low-risk neonates (unshaded bars) using nonparametric Mann Whitney U test. Significance values are shown as *p < 0.01; **p < 0.05.