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Table 1 Determination of Specific IgE and IgG Antibodies in Subjects With Isocyanate-induced Asthma

From: Update on the Pathogenic Mechanisms of Isocyanate-induced Asthma

   Specific
IgE (%)
Specific
IgG (%)
Authors (yr) Assay Se Sp Se Sp
Butcher BT et al (1980) [42] RAST 19 -- -- --
Pezzini A et al (1984) [43] RAST 39 -- -- --
Keskinen H et al (1988) [44] RAST 20 -- -- --
Cartier A et al (1989) [21] ELISA 31 97 72 76
Karol MH et al (1994) [45] RAST 3 93 3 93
Tee RD et al (1998) [7] RAST ratio > 2 28 92 -- --
  RAST ratio > 3 20 100 -- --
Park HS et al (1999) [18] ELISA 14 92 46 92
Bernstein DI et al (2002) [28] ELISA 21 89 47 74
Ye YM et al (2006) [20] ELISA 43.9 -- 30.3 --
  1. RAST indicates radioallergosorbent test; ELISA, enzyme-linked immunosorbent assay; Se, sensitivity; Sp, specificity.